Axios

Chronic cannabis users suffering from cannabis hyperemesis syndrome can now be formally diagnosed.

Why it matters: The World Health Organization's recent move to formally name the condition — which includes symptoms such as nausea and vomiting — gives doctors the chance to track prevalence and get a better picture of adverse events.

The meeting between President Trump and Saudi Crown Prince Mohammed bin Salman (MBS) last week got heated when they discussed the possibility of Saudi Arabia joining the Abraham Accords and normalizing relations with Israel, two U.S. officials and one source with knowledge of the situation told Axios.

Why it matters: With the war in Gaza over, Trump hoped his meeting with MBS would lead to a breakthrough toward Saudi-Israeli normalization.

Ukrainian President Volodymyr Zelensky wants to meet President Trump "as soon as possible" — possibly over Thanksgiving — to finalize a joint U.S.-Ukrainian agreement on the terms for ending the war, Zelensky's chief of staff Andriy Yermak told Axios.

Why it matters: U.S. and Ukrainian officials have agreed in principle on most aspects of the plan, which has been modified heavily from the initial 28-point U.S. proposal. But Zelensky wants to negotiate on the matter of territorial concessions with Trump himself, Yermak said.

Lukoil is Russia's second largest oil company, with global operations stretching from extraction fields in Iraq to gas stations in Pennsylvania.

• It's also got a financial gun to its head, due to U.S. sanctions that are set to take effect in less than two weeks, prompting it to put its international operations up for sale.

Army Secretary Dan Driscoll is holding talks with Russian officials in Abu Dhabi after U.S. negotiators reached initial understandings with Ukraine on a draft peace plan, according to a U.S. official and a source with knowledge.

Why it matters: It's been a week of chaotic diplomacy since Axios revealed the plan last Tuesday, with Ukraine first alarmed by the U.S. plan and then optimistic about revisions secured during talks in Geneva. After reaching an "updated and refined peace framework" with Ukraine, the Trump administration is now pivoting to try to get Russia on board.

Zipline says it will receive up to $150 million from the U.S. State Department to expand drone deliveries of blood, vaccines and other medical supplies in five African countries.

Why it matters: The contract represents an early example of the Trump administration's new "America First" foreign assistance agenda, touted in July by Secretary of State Marco Rubio, following its decision to shut down the U.S. Agency for International Development (USAID).

Russia launched a series of strikes on Ukraine's capital, Kyiv, early Tuesday and killed at least two people, the city's mayor said.

The big picture: The bombardment on the 1,371th day of Putin's war on Ukraine comes as U.S. and Ukrainian officials report progress in Geneva talks on President Trump's plan for peace.

Jakarta is now the biggest city in the world.

The big picture: It's what is known as a megacity, population-dense hubs that are becoming more frequent across the globe. Per a new report from the United Nations, approximately 45% of the world's population lives in a city, and Jakarta is home to nearly 42 million.

Latinos feel historic levels of pessimism about their place in the U.S., their economic stability and the impact of President Trump's second-term policies, a new Pew Research Center survey found.

Why it matters: The findings mark some of the bleakest assessments by Latinos in nearly two decades of Pew surveys and confirm similar findings in an Axios-Ipsos poll released this month.

From Ukraine to Gaza, MAGA has made it clear: clinching a deal to end foreign fighting matters far more than the fine print.

Why it matters: This non-ideological approach to foreign policy explains why President Trump has faced little political pressure from his base as he's sought to broker an end to the world's most intractable conflicts.

President Trump said Monday that he'd accepted an invitation from President Xi Jinping to visit Beijing in April. He added that he'd invited the Chinese leader for a state visit later in 2026.

Why it matters: Both leaders have an interest in maintaining an equilibrium in the relationship after last month's trade truce. But with Xi ramping up his rhetoric on taking Taiwan — and with trade disputes in areas like mineral and chip exports still not fully resolved — there's always a lot at stake when the world's two most powerful leaders meet.

The COP30 summit's conclusion in Brazil leaves the future of global climate diplomacy at another crossroads.

Why it matters: These annual UN summits are meant to breathe ever more life into the Paris Agreement's goals as Earth gets dangerously hotter.

New Instacart data shared with Axios shows the most uniquely popular Thanksgiving pies by state, based on last year's orders.

What they found: Pumpkin pie is big out West, strawberry rhubarb and French silk are favorites in the Midwest, and cream pies are a hit in New England.

President Volodymyr Zelensky listened on speakerphone one week ago as President Trump's advisers Steve Witkoff and Jared Kushner read, line by line, from a 28-point plan to end the war in Ukraine.

Why it matters: The existence of the plan would emerge two days later on Axios. By Friday, Zelensky was warning the Ukrainian people that Trump's plan — and the pressure he faced to sign it — had plunged Ukraine into one of the most difficult moments of its existence.

The number of war crime investigations open in Ukraine at the start of the fall was 178,391, Ukrainian prosecutor Vitalii Dovhal told CBS' "60 Minutes" in a program airing Sunday evening.

The big picture: The revelation comes as Ukrainian and U.S. officials hold talks on President Trump's 28-point peace plan that would force Kyiv to make concessions including ceding additional territory to Russia's invading forces and accepting full amnesty for Russians accused of war crimes.

Multiple international airlines canceled flights to Venezuela over the weekend after the Federal Aviation Administration warned of a "worsening security situation" in the South American country amid a U.S. military buildup in the region.

The big picture: The FAA, in a Friday NOTAM (Notice to Airmen) warning of "heightened military activity" in the region, has seen at least six airlines cancel flights, Marisela de Loaiza, president of the Airlines Association in Venezuela (ALAV), told media Sunday.