1. Global: Total confirmed cases as of 9:30 p.m. ET: 31,467,508 — Total deaths: 967,881— Total recoveries: 21,583,915 — Map.
2. U.S.: Total confirmed cases as of 9:30 p.m. ET: 6,890,662 — Total deaths: 200,710 — Total recoveries: 2,646,959 — Total tests: 96,612,436 — Map.
3. Health: The U.S. reaches 200,000 coronavirus deaths — The CDC's crumbling reputation — America turns against coronavirus vaccine.
4. Politics: Elected officials are failing us on much-needed stimulus.
5. Business: Two-thirds of business leaders think pandemic will lead to permanent changes — Fed chair warns economy will feel the weight of expired stimulus.
6. Sports: NFL fines maskless coaches.

GoodRx, a price comparison app for prescription drugs at local pharmacies, on Tuesday night raised $1.14 billion in its IPO, Axios has learned.

By the numbers: GoodRx priced its shares at $33 a piece, above its $24-$28 per share offering range, which will give it an initial market cap of around $12.7 billion.

Today marks another devastating milestone in the 2020 history books:

The state of play: February 29: First reported U.S. coronavirus death; May 23: U.S. death toll hits 100,000; September 22: U.S. death toll hits 200,000, according to the Johns Hopkins tracker.

The Centers for Disease Control and Prevention issued holiday-specific guidelines this week to limit COVID-19 risks posed by gatherings and celebrations prior to the fall and winter holidays.

Why it matters: With the flu season just around the corner, medical experts are worried about the likelihood of battling COVID-19 and influenza at the same time. The coronavirus has now killed 200,000 Americans, and the U.S. is averaging roughly 830 per day. Cases and deaths could worsen again as the weather gets colder and people move indoors.

About 20% of Dunkin' Brands' customer transactions are digital in some form, Kate Jaspon, the company's chief financial officer, said Tuesday during an Axios virtual event.

Why it matters: Many restaurants and fast-food chains have had to drastically change or speed up their investment in technology services to make orders hands-free, cashless and safer for customers and workers during the coronavirus pandemic.

The coronavirus has now killed 200,000 Americans, according to Johns Hopkins data.

The big picture: Whatever context you try to put this in, it is a catastrophe of historic proportions — and is yet another reminder of America's horrific failure to contain the virus.

The NFL is imposing fines of $100,000 per coach and $250,000 per club for violations of the league's mask policy, AP reports.

The state of play: The first three to get fined were Denver's Vic Fangio, San Francisco's Kyle Shanahan and Seattle's Pete Carroll.

Health care wasn't the top issue heading into the 2020 election — and then Ruth Bader Ginsburg died.

Between the lines: This poll was conducted in the days before her death, which has significantly increased the threat to the Affordable Care Act and thus the threat to the law's pre-existing conditions protections.

America's elected representatives have failed America.

Why it matters: The bipartisan inability to deliver economic stimulus could impede economic growth for months to come. It will create widespread damage across America — from small businesses to large industries to schools and day cares — and leave many Americans without jobs or homes.

The share of Americans eager to try a first-generation coronavirus vaccine dropped significantly in the latest installment of the Axios-Ipsos Coronavirus Index, as President Trump hyped suggestions that one could be ready before the election.

Why it matters: As the U.S. reaches a milestone of 200,000 deaths, this underscores the risks of politicizing the virus and its treatments.

The Centers for Disease Control and Prevention abruptly removed new guidance saying that the coronavirus spreads via aerosols from its website yesterday, drawing a fresh barrage of criticism.

The big picture: Concerns about the CDC's competence and politicization have only grown as the pandemic rages on.

Some 90,000 New York City children in pre-K and those with advanced disabilities went back to school for in-person classes on Monday.

The big picture: All other students in the city resumed classes online. Elementary schools are due to open on Sept. 29, with middle schools and high schools following on Oct. 1.

A coalition of 156 countries agreed Monday to a "landmark" agreement aimed at the fair distribution of COVID-19 vaccines around the globe, the World Health Organization announced Monday.

The big picture: 64 higher-income countries, including European Union members, are among the signatories to the deal, known as "COVAX." The U.S. is not participating in the scheme.