The coronavirus outbreak will likely cause a drop in global carbon dioxide emissions that's far larger than any prior crisis or war, per a new analysis that combines multiple datasets to provide a wide-ranging look at the pandemic's effect.

What they found: The analysis from the U.K.-based Carbon Brief provides a tentative estimate that global CO2 emissions are likely to fall by more than 4% from 2019 levels.

Premier League players have launched an initiative called #PlayersTogether, which will funnel part of their salaries to the National Health Service to support the U.K.'s front-line workers during the coronavirus crisis.

Why it matters: This decision came at the conclusion of a protracted argument between players, clubs and even government officials over who should bear the brunt of lost revenue in the midst of the pandemic.

Some market analysts and economists have gotten wary of the Fed's expanding laundry list of asset purchases.

Why it matters: The big worry for most is that the Fed is now manipulating larger and larger swaths of what is supposed to be a free market.

Wall Street seems to unanimously approve of the Federal Reserve's actions so far, but most Americans are less enthused, a new poll from data firm CivicScience provided for Axios shows.

The state of play: The data shows that just 12% of respondents say they think the Fed has done "very well" in its response to the coronavirus outbreak, while 19% say the Fed has done "very poorly."

In terms of regulatory flexibility, the FDA's approach to coronavirus antibody testing is a 180-degree turn from its approach to diagnostic testing.

The big picture: The antibody tests, also known as serological tests, essentially detect whether someone's immune system has reacted to the coronavirus, helping determine whether they have had it — regardless of whether they had symptoms.

Republicans are increasingly concerned not only about President Trump’s daily briefings but also his broader plan to ease the nation out of the virus crisis and back to work. This concern is acute — and spreading. 

Why it matters: Trump can easily address the briefing worries by doing fewer, but the lackluster bounce-back planning is what worries Republicans most. 

The first hospital network in the U.S. has joined an international clinical trial using artificial intelligence to help determine which treatments for patients with the novel coronavirus are most effective on an on-going basis.

Why it matters: In the midst of a pandemic, scientists face dueling needs: to find treatments quickly and to ensure they are safe and effective. By using this new type of adaptive platform, doctors hope to collect clinical data that will help more quickly determine what actually works.

It feels like some big, terrible switch got flipped when the coronavirus upended our lives — so it’s natural to want to simply flip it back. But that is not how the return to normalcy will go.

The big picture: Even as the number of illnesses and deaths in the U.S. start to fall, and we start to think about leaving the house again, the way forward will likely be slow and uneven. This may feel like it all happened suddenly, but it won't end that way.

Commercial labs are in a precarious financial position, as the overwhelming demand for coronavirus tests is not close to making up the revenue of other tests that aren't being ordered.

Why it matters: Commercial labs are anchoring coronavirus testing, and testing remains paramount to mitigating the spread of the coronavirus.

Early missteps allowed the new coronavirus to spread throughout the U.S for weeks before state and local officials implemented strict lockdowns designed to keep the pandemic from spinning further out of control.

Why it matters: The U.S. missed the boat on the kind of swift, early response that would have been most effective, and has been scrambling to catch up ever since. This timeline, compiled from official sources as well as media reports, shows how that all-important time was lost.

1. Global: Total confirmed cases as of 8 a.m. ET: 1,612,646 — Total deaths: 96,787 — Total recoveries: 361,377 — Map.
2. U.S.: Total confirmed cases as of 8 a.m. ET: 466,299 — Total deaths: 16,686 — Total recoveries: 26,522 — Map.
3. 2020 latest: Republicans are getting worried about President Trump's daily briefings and his eventual plan to restart the economy.
4. Business latest: The auto industry is sharing detailed return-to-work guidelines on how to shield employees from the coronavirus.
5. Public health latest: The U.S. has expelled thousands of migrants under a CDC public health order.
6. Timeline: How the U.S. fell behind
7. What should I do? Hydroxychloroquine questions answered — Pets, moving and personal health — Answers about the virus from Axios experts — What to know about social distancing — Q&A: Minimizing your coronavirus risk.
8. Other resources: CDC on how to avoid the virus, what to do if you get it.

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The auto industry is sharing detailed return-to-work guidelines on how to shield employees from the coronavirus as it prepares to reopen its own factories in the coming weeks.

Why it matters: We might not shake hands again, but sooner or later, most of us will return to our jobs, whether in a factory, office or public venue within close proximity of others. Reestablishing an environment where employees feel comfortable and can remain healthy will be a daunting challenge for every employer.

For the past two days, the coronavirus has killed more than 2,000 people in the U.S. within 24 hour periods. But on Thursday, the single-day death toll did not exceed 2,000, per per Johns Hopkins data.

Where it stands: Roughly 16 million Americans have filed for jobless benefits over the past three weeks due to the pandemic's growing economic repercussions. Here's how to understand the scale of American job decimation.

Georgia's primary election will be postponed until June 9, Secretary of State Brad Raffensperger said Thursday, after the state initially moved its primary to May.

Why it matters: 23 other states and the District of Columbia haven't held primaries yet. The White House is recommending, for now, that Americans practice social distancing and gather in groups of no more than 10 people — while over 40 states have issued stay-at-home orders.