CRISPR

Trying to eradicate malaria around the world


Data: The Malaria Atlas Project; Map: Harry Stevens/Axios

The fight against malaria in the past couple decades has largely had a positive trajectory — since 2000, there have been 7 million lives saved and about 1 billion cases prevented — but recently there's been pockets of plateauing or increased infections in the world.

Why it matters: Malaria parasites are starting to show more resistance against insecticides and drug treatments. Combined with political instability and lack of necessary funding, the goal of eliminating malaria now requires urgent action with new tools no longer using the "one size fits all" method, a group of malaria experts tell Axios.

Research deepens on using "jumping genes" in CRISPR therapy

Illustration: Rebecca Zisser/Axios

Two prominent teams of scientists recently announced transposons — or "jumping genes" — can improve the precision of CRISPR gene editing.

Why it matters: While this research is still in early stages, as both teams tested their techniques on bacterial cells, experts say the technique could allow edited genes to be more precisely inserted into genomes, possibly addressing concerns with current CRISPR systems that can lead to off-target editing and random deletions or even cancer.