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Lauryn Morley, a lower school substitute teacher for the Washington Waldorf School in Bethesda, Maryland, works from her home in Arlington, Virginia. Photo: Olivier Douliery/AFP via Getty Images

The number of novel coronavirus cases in the U.S. has grown from one on Jan. 21 to more than 312,000 by early Sunday, per Johns Hopkins.

The big picture: Roughly three-quarters of the American population is on lockdown, with social distancing measures and other orders in place across the country. Here's how Americans are coping with the massive upheaval the outbreak has brought, in photos.

Miami residents applaud from their balconies in solidarity for health care workers, first responders, supermarket employees and all the professions helping to fight COVID-19. Photo: Chandan Khanna/AFP via Getty Images
A sanitation station in Philadelphia. Photo: Cory Clark/NurPhoto via Getty Images
The Samaritan's Purse emergency field hospital for coronavirus patients in New York City's Central Park. Photo: Bryan R. Smith/AFP via Getty Images
Cellist Jodi Beder performs a daily concert on her front porch in Mount Rainier, Maryland, to help people passing by and her neighbors cope with the outbreak. Photo: Andrew Caballero-Reynolds/AFP via Getty Images
Martha's Table volunteer Poet Taylor helps distribute hundreds of free hot meals to people in need in Washington, D.C. Photo: Chip Somodevilla/Getty Images
O'Hare International Airport in Chicago, which typically serves 8.2 million passengers a month, has closed two of its seven runways as the pandemic has significantly reduced air travel. Photo: Scott Olson/Getty Images
People keep to social distancing guidelines in Portland, Oregon. Photo: Alex Milan Tracy/Anadolu Agency via Getty Images
Signs are posted throughout Long Beach, California, reminding residents of what areas are closed. Photo: Brittany Murray/MediaNews Group/Long Beach Press-Telegram via Getty Images
A police officer outside the closed Alamo in San Antonio, Texas. Photo: Mark Felix/AFP via Getty Images
U.S. Customs officers at the U.S.-Canada border in Lansdowne, Ontario. Photo: Lars Hagberg/AFP via Getty Images
The L.L. Bean plant in Brunswick, Maine, has begun producing safety masks during the COVID-19 epidemic. Photo: Blake Nissen for The Boston Globe via Getty Images
A police officer at the entrance to a coronavirus testing center in Hansen Dam Park, Pacoima, California. Photo: Frederic J. Brown/AFP via Getty Images
People around the world have been placing stuffed bears in their windows to keep kids entertained during the outbreak — including this house in Boston's Hyde Park. Photo: Lane Turner/The Boston Globe via Getty Images

Go deeper: What a coronavirus exit ramp looks like

Go deeper

Oct 27, 2020 - World

Putin mandates face masks as Russia combats second COVID-19 wave

Russian President Vladimir Putin. Photo: Alexei Druzhinin/Sputnik/AFP via Getty Images

Russian President Vladimir Putin on Tuesday instituted a nationwide mask mandate, as the nation tries to combat a second spike of COVID-19 cases, according to an order published by Rospotrebnadzor, the federal health watchdog agency.

By the numbers: Russia currently has the fourth-most coronavirus cases in the world, with 1,537,142, according to Johns Hopkins data, behind the U.S., India and Brazil. Russia has reported 26,092 deaths to date.

Updated 26 mins ago - Politics & Policy

Coronavirus dashboard

Illustration: Sarah Grillo/Axios

  1. Health: WHO: AstraZeneca vaccine must be evaluated on "more than a press release."
  2. Politics: Supreme Court backs religious groups on New York COVID restrictions.
  3. World: Thailand, Philippines sign deal with AstraZeneca for vaccine.
  4. Economy: Safety nets to disappear in December Black Friday shopping across the U.S., in photosAmazon hires 1,400 workers a day throughout pandemic.
  5. Education: National standardized tests delayed until 2022.

Scoop: Biden weighs retired general Lloyd Austin for Pentagon chief

Lloyd Austin testifying before Congress in 2015. Photo: Chip Somodevilla/Getty Images

Joe Biden is considering retired four-star general Lloyd Austin as his nominee for Defense secretary, adding him to a shortlist that includes Jeh Johnson, Tammy Duckworth and Michele Flournoy, two sources with direct knowledge of the decision-making tell Axios.

Why it matters: A nominee for Pentagon chief was noticeably absent when the president-elect rolled out his national security team Tuesday. Flournoy had been widely seen as the likely pick, but Axios is told other factors — race, experience, Biden's comfort level — have come into play.