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Democratic presidential candidates Sen. Elizabeth Warren, Tom Steyer and Sen. Bernie Sanders during a heated exchange at the debate at Drake University in Des Moines. Photo: Robyn Beck/AFP via Getty Images

Sen. Elizabeth Warren appeared to reject Democratic presidential rival Sen. Bernie Sanders' handshake after the progressive pair clashed during Tuesday night's debate in Des Moines, Iowa.

Driving the news: The longtime friends were at loggerheads during the debate on the North American trade deal and whether Sanders said a woman could be elected president. Here's what else unfolded, in photos.

Former Vice President Joe Biden speaks as Sanders and former South Bend Mayor Pete Buttigieg listen. Photo: Scott Olson/Getty Images
Buttigieg and Sen. Amy Klobuchar during the debate. Photo: Scott Olson/Getty Images
Biden greets Sanders. Photo: Scott Olson/Getty Images
Buttigieg hugs his husband, Chasten Buttigieg. Photo: Scott Olson/Getty Image
Warren, Biden and Sanders were all smiles before the debate. Photo: Scott Olson/Getty Images
Steyer, Warren, Biden, Sanders, Buttigieg and Klobuchar line up before the debate. Photo: Spencer Platt/Getty Images
Go deeper:

Go deeper

Mayors press Biden to adopt progressive immigration agenda

Illustration: Sarah Grillo/Axios

A coalition of nearly 200 mayors and county executives is challenging Joe Biden and the incoming Congress to adopt a progressive immigration agenda that would give everyone a pathway to citizenship.

Why it matters: The group's goals, set out in a white paper released today, seem to fall slightly to the left of what the president-elect plans to propose on Inauguration Day — though not far — and come at a time of intense national polarization over immigration.

Caitlin Owens, author of Vitals
14 mins ago - Health

Demand for coronavirus vaccines is outstripping supply

Illustration: Aïda Amer/Axios

Now that nearly half of the U.S. population could be eligible for coronavirus vaccines, America is facing the problem experts thought we’d have all along: demand for the vaccine is outstripping supply.

Why it matters: The Trump administration’s call for states to open up vaccine access to all Americans 65 and older and adults with pre-existing conditions may have helped massage out some bottlenecks in the distribution process, but it’s also led to a different kind of chaos.

Woman who allegedly stole laptop from Pelosi's office to sell to Russia is arrested

Photo: FBI

A woman accused of breaching the Capitol and planning to sell to Russia a laptop or hard drive she allegedly stole from Speaker Nancy Pelosi's office was arrested in Pennsylvania's Middle District Monday, the Department of Justice said.

Driving the news: Riley June Williams, 22, is charged with illegally entering the Capitol as well as violent entry and disorderly conduct. She has not been charged over the laptop allegation and the case remains under investigation, per the DOJ.