As the economy adapts to a new era powered by remote work, some jobs are at risk of not coming back at all, Nathan writes.

Why it matters: We're still grappling with the ramifications from the seismic economic changes wrought by the pandemic.

• Meanwhile, large swaths of the workforce are still working remotely, which has negative implications for jobs reliant on office worker traffic.

Driving the news: Facebook parent Meta is reducing contract positions at several transportation firms that shuttled workers to its offices, CNBC reported today.

Threat level: Jobs that relied on people coming to the office regularly are most at risk.

What they're saying: The trend is especially acute at offices in sectors that have bet big on remote work, Lightcast senior economist Rucha Vankudre tells Axios.

• "It's jobs like surveillance officer, mailroom worker, office technician, office manager, administrative assistant — all of the jobs that make these large tech and finance offices work are really where we think remote work is going to work against us," Vankudre says.

Zoom in: Many of these positions do not require a college degree, meaning their elimination tends to hit folks with lower incomes the hardest.

• The number of employed civilians 25 and up with only a high school diploma fell by 3.5% from pre-pandemic September 2019 to September 2022, according to the Bureau of Labor Statistics.

The bottom line: Remote work is rattling support staff that previously relied heavily on people commuting to the workplace.

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Median rent fell for the first time in 2022 on a month-to-month basis as shelter inflation cools off, Nathan writes.

By the numbers: Rent fell by 2.5% from August to September, according to a new report by Rent.com, which called it "a hopeful sign that the rental market is stabilizing" after a run of steep increases.

• Yes, but: Prices were still up 8.8% year over year, though that's the smallest such increase since October 2021.

💸 The IRS is raising the contribution limits for 401(k) plans. (Axios)

📉 The dollar fell compared with the yen as traders brace for Japanese intervention. (Reuters)

🎵 Taylor Swift's "Midnights" album release briefly crashed Spotify. (Bloomberg)

Pfizer plans to charge $110–$130 per dose for its COVID-19 vaccine once government purchases end next year, Axios senior health care editor Adriel Bettelheim reports.

The big picture: Weak demand for the shots and private market pressures were expected to cost manufacturers billions once government purchases end. Price increases, while expected, could lead to higher insurance premiums.

• The government now pays about $30 a dose to Pfizer and its partner BioNTech.

Catch up quick: Next year, Americans will lose free access to government-funded COVID tests, treatments and vaccines. The cost will begin to be transferred to patients through premiums and out-of-pocket costs.

What we're watching: While vaccines will continue to be available to virtually anyone with public and private insurance in a private market, it's not clear how much access the uninsured will have.

Go deeper.

All eyes are on "Black Adam," the DC Comics-inspired vehicle starring Dwayne “The Rock” Johnson as the titular antihero, which officially opens today.

Why it matters: The stakes couldn’t be higher for Warner/Discovery, which has alienated legions of DC fans by canceling and postponing several high-profile projects, Axios’ Javier E. David writes.

The intrigue: Current projections expect the movie to pull in something north of $60 million this weekend, Deadline reported, but that’s below other major tentpoles.

What they’re saying: Some of the more unforgiving reviewers use words like “humdrum,” “clumsy,” and “brainless” (ouch). Still, the comparatively higher audience scores may yet give “Black Adam” an unexpected box office boost.

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"Musk cannot cut his way to growth with Twitter, and a number in the 75% zip code would be way too aggressive ... and potentially set back this core platform for years."