Jun 6, 2025 - News
These are Massachusetts' Fortune 500 companies
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Massachusetts is home to 18 companies listed by Fortune as among the 500 largest in the nation.
Why it matters: The Massachusetts economy is largely powered by medicine and higher education, and the industries connected to them.
- Some of the state's biggest players aren't associated with eds and meds, but they still have hundreds or thousands of employees in the Bay State.
Zoom out: Some global brands with Massachusetts roots are well-known to consumers, like GE, T.J.Maxx, Keurig Dr Pepper and Wayfair.
Follow the money: Massachusetts has deep connections to global finance as well, with Liberty Mutual, MassMutual and State Street among the biggest investment operations in the country.
And then there are the life science giants like Biogen, Thermo Fisher and Vertex on the cutting edge of research and earnings.