Sign up for our daily briefing

Make your busy days simpler with Axios AM/PM. Catch up on what's new and why it matters in just 5 minutes.

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Stay on top of the latest market trends

Subscribe to Axios Markets for the latest market trends and economic insights. Sign up for free.

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Sports news worthy of your time

Binge on the stats and stories that drive the sports world with Axios Sports. Sign up for free.

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Tech news worthy of your time

Get our smart take on technology from the Valley and D.C. with Axios Login. Sign up for free.

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Get the inside stories

Get an insider's guide to the new White House with Axios Sneak Peek. Sign up for free.

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Catch up on coronavirus stories and special reports, curated by Mike Allen everyday

Catch up on coronavirus stories and special reports, curated by Mike Allen everyday

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Want a daily digest of the top Denver news?

Get a daily digest of the most important stories affecting your hometown with Axios Denver

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Want a daily digest of the top Des Moines news?

Get a daily digest of the most important stories affecting your hometown with Axios Des Moines

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Want a daily digest of the top Twin Cities news?

Get a daily digest of the most important stories affecting your hometown with Axios Twin Cities

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Want a daily digest of the top Tampa Bay news?

Get a daily digest of the most important stories affecting your hometown with Axios Tampa Bay

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Want a daily digest of the top Charlotte news?

Get a daily digest of the most important stories affecting your hometown with Axios Charlotte

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Electron microscope photo of EV-D68, a suspect in causing AFM. Photo: Cynthia S. Goldsmith, Yiting Zhang/CDC

The CDC on Tuesday warned of an expected uptick in cases of acute flaccid myelitis (AFM), a rare polio-like illness that can disable and sometimes kill children.

Why it matters: The agency cautioned parents to overcome any reluctance driven by the coronavirus pandemic and urgently bring their kids to the hospital should they suspect a case — especially if they exhibit a telltale symptom like limb weakness.

  • Based on evidence collected since 2014 by the CDC, AFM experiences an uptick every other year, and is expected to recur from now through November.
  • Scientists are still hunting down the cause of AFM, but CDC officials expressed concern parents may delay seeking medical help when "early and aggressive" therapy is needed as soon as possible.
  • As of July 31, 16 cases were confirmed and 38 were under investigation.

What they're saying: "Unfortunately, many kids with AFM will have permanent disability," said Thomas Clark, the deputy director of the CDC's viral diseases division, at a press briefing.

  • "It's really important that kids get into rehabilitation — early and aggressive physical therapy [and] occupational therapy can help strengthen the function that they do retain, and help them go about their lives with the best functioning possible," he added.

By the numbers: Clark and CDC Director Robert Redfield discussed the findings of the agency's latest Vital Signs report. It examined evidence from the 2018 season, which had 238 confirmed patients who had a median age of 5.3 years old.

  • Most (92%) had a fever, respiratory illness or both before the onset of weakness.
  • In addition to weakness, common symptoms include gait difficulty (52%), neck or back pain (47%), fever (35%) and limb pain (34%).
  • Among the 211 who were outpatients when the weakness began, 64% sought treatment at an emergency department.
  • 23% required intubation and mechanical ventilation.

How it works: Researchers continue seeking the cause, although "most patients" had the enterovirus EV-D68 in their system. However, there was a cluster in Colorado that had EV-A71 — and not all patients show either enterovirus.

  • A possible vaccine for EV-D68 is in preclinical phase trials, Redfield said.

Go deeper:

Go deeper

CDC official: Pandemic "explosion" of antibiotic resistance not seen

Illustration: Sarah Grillo/Axios

Despite concerns over antimicrobial resistance flourishing during the pandemic as doctors use all their tools to help patients fight COVID-19, early indications are that their efforts may not be causing a large increase, a CDC official tells Axios.

Why it matters: AMR is a growing problem, as the misuse or overuse of antibiotics creates resistant pathogens that cause more than 2.8 million infections and 35,000 deaths annually in the U.S.

46 mins ago - World

Netanyahu campaigns against Biden's plan to save Iran deal

Netanyahu campaigns at a gym last month. Photo: Pool/AFP via Getty

Israeli Prime Minister Benjamin Netanyahu indirectly criticized the Biden administration for its intention to return to the Iran nuclear deal and told his supporters he was prepared to "stand against the entire world" to stop it.

Why it matters: This is a major change of tune for Netanyahu, who had been careful in his statements on the Iran deal and avoided publicly criticizing President Biden. The statement was part of Netanyahu's attempt to rally his base ahead of Israel's election on March 23.

Updated 1 hour ago - Politics & Policy

Coronavirus dashboard

Illustration: Aïda Amer/Axios

  1. Tech: "Fludemic" model accurately maps COVID hotspotsVirtual doctor's visits and digital health tools take off.
  2. Politics: Schumer says Senate will stay through weekend to vote on COVID relief — Republican governor of West Virginia says there's no plan to lift mask mandate.
  3. World: Canada vaccine panel recommends 4 months between doses.
  4. Business: Firms develop new ways to inoculate the public.
  5. Local: Ultra-rich Florida community got vaccinations in January.