Stories by Eileen Drage O'Reilly

With antibiotic resistance growing, WHO promotes monitoring tool

Illustration: Sarah Grillo/Axios

Due to the lack of new antibiotics in the pipeline, current drugs must be better monitored and prescribed before the problem of antimicrobial resistance (AMR) reaches a "Titanic" stage, World Health Organization scientists warned Tuesday as they launch a campaign to promote the use of a monitoring tool, AWaRe.

Why it matters: The growing level of superbugs is a potentially "catastrophic" global threat that could have a yearly death toll of 10 million people by 2050. WHO says using AWaRe would be one tool in promoting its goal that 60% of all antibiotics used come from the "access" category of antibiotics, or what's typically thought of as the first or second line of defense.

Research deepens on using "jumping genes" in CRISPR therapy

Illustration: Rebecca Zisser/Axios

Two prominent teams of scientists recently announced transposons — or "jumping genes" — can improve the precision of CRISPR gene editing.

Why it matters: While this research is still in early stages, as both teams tested their techniques on bacterial cells, experts say the technique could allow edited genes to be more precisely inserted into genomes, possibly addressing concerns with current CRISPR systems that can lead to off-target editing and random deletions or even cancer.

In contrast to others, WHO offers cautious hope on Ebola outbreak

DRC Ministry of Health; Chart: Andrew Witherspoon, Harry Stevens/Axios

The World Health Organization said Thursday there should be cautious hope at signs the numbers of confirmed Ebola cases and the geographical footprint have lessened over the past couple weeks in the Democratic Republic of the Congo.

The other side: This is in sharp contrast to what other experts and organizations have been saying, with the head of the Centers for Disease Control warning at a hearing that he anticipates the deadly virus will spread outside the DRC and multiple international health officials calling for a "reset."