1. We're the architects of our own COVID destiny
We're almost certainly going to have to live with the coronavirus, in some form, for the foreseeable future. But what that means will be shaped in large part by what we do now.
Why it matters: More than half of the world — and a substantial portion of Americans — remains unvaccinated. Getting these rates up could mean the difference between the virus becoming a back-burner nuisance, or something that continues to define our lives for years to come.