Photo: Kirsty Wigglesworth/AP

An image of the clock face of Big Ben was projected on 10 Downing Street, residence of British Prime Minister Boris Johnson, as Britain officially left the European Union at 11 p.m. London time.

Why it matters: "In its biggest shift since losing its global empire, [the U.K. turns] its back after 47 years on the post-World War Two project that sought to build the ruined nations of Europe into a global power," Reuters writes.

  • "Brexit parties were held in some pubs and social clubs as well as in London's Parliament Square [below], as the country counted down." (BBC)
Photo: Jeff Mitchell/Getty Images

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Updated 13 mins ago - Politics & Policy

Coronavirus dashboard

Illustration: Annelise Capossela/Axios

  1. Global: Total confirmed cases as of 6:30 p.m. ET: 20,177,521 — Total deaths: 738,716 — Total recoveries: 12,400,156Map.
  2. U.S.: Total confirmed cases as of 6:30 p.m. ET: 5,130,784 — Total deaths: 164,603 — Total recoveries: 1,670,755 — Total tests: 62,513,174Map.
  3. States: Georgia reports 137 coronavirus deaths, setting new daily record Florida reports another daily record for deaths.
  4. Health care: Trump administration buys 100 million doses of Moderna's coronavirus vaccine.
  5. Business: Moderna reveals it may not hold patent rights for vaccine.
  6. Sports: Big Ten scraps fall football season.

Voters cast ballots in Minnesota, Georgia, Connecticut, Wisconsin and Vermont

Photo: Spencer Platt/Getty Images

Primary elections are being held on Tuesday in Minnesota, Georgia, Connecticut, Vermont and Wisconsin.

The big picture: Georgia and Wisconsin both struggled to hold primaries during the coronavirus pandemic, but are doing so again — testing their voting systems ahead of the general election. Rep. Ilhan Omar (D-Minn.) is facing a strong challenger as she fights for her political career. In Georgia, a Republican primary runoff pits a QAnon supporter against a hardline conservative.

42 mins ago - Health

Trump administration buys 100 million doses of Moderna's vaccine

A volunteer in Moderna's vaccine clinical trial receives a shot. Photo: Paul Hennessy/NurPhoto via Getty Images

The U.S. government has agreed to buy 100 million doses of Moderna's experimental coronavirus vaccine for $1.5 billion, or $15 per dose.

Why it matters: The Trump administration, through Operation Warp Speed, has now bought initial batches of vaccines from Moderna, GlaxoSmithKline and Sanofi, Pfizer, Novavax, Johnson & Johnson and AstraZeneca before knowing whether they are safe and effective. The federal government also appears to own some of the patent rights associated with Moderna's vaccine.