Searching for smart, safe news you can TRUST?

Support safe, smart, REAL journalism. Sign up for our Axios AM & PM newsletters and get smarter, faster.

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Searching for smart, safe news you can TRUST?

Support safe, smart, REAL journalism. Sign up for our Axios AM & PM newsletters and get smarter, faster.

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Denver news in your inbox

Catch up on the most important stories affecting your hometown with Axios Denver

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Des Moines news in your inbox

Catch up on the most important stories affecting your hometown with Axios Des Moines

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Minneapolis-St. Paul news in your inbox

Catch up on the most important stories affecting your hometown with Axios Minneapolis-St. Paul

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Tampa-St. Petersburg news in your inbox

Catch up on the most important stories affecting your hometown with Axios Tampa-St. Petersburg

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

People queuing at to enter a grocery story in Adelaide, South Australia, on Wednesday ahead of the midnight lockdown. Photo: Kelly Barnes/Getty Images

South Australia will enter a "circuit breaker" lockdown overnight in an attempt to quash a COVID-19 outbreak, state Premier Steven Marshall announced Wednesday, saying: "We are going hard and we are going early. Time is of the essence."

The big picture: 36 new coronavirus infections have been confirmed since the first community case for six months was detected in state capital Adelaide Sunday. All schools, construction, bars and eateries must close for six days from midnight. Only one person per household can leave home each day and exercise outside is prohibited under the rules. Regional travel and fast food delivery are both banned.

Go deeper: Australian city Melbourne to exit one of world's longest lockdowns

Go deeper

Updated 7 hours ago - World

Oxford University says its coronavirus vaccine is up to 90% effective

A scientist working during at the Oxford Vaccine Group's laboratory facility at the Churchill Hospital in Oxford, England, in June. Photo: Steve Parsons/Pool/AFP via Getty Images

The University of Oxford announced Monday that a COVID-19 vaccine it's developed with AstraZeneca is 70.4% effective in preventing people from developing symptoms, per interim data from Phase 3 trials.

Why it matters: The Oxford-AstraZeneca vaccine is shown to work in different age groups and can be stored at fridge temperature. It is much cheaper than other vaccines in development and is part of the global COVAX initiative, designed to ensure doses go where they're most needed.

10 hours ago - Politics & Policy

California governor and family in quarantine after coronavirus exposure

California Gov. Gavin Newsom. Photo: Justin Sullivan/Getty Images

California Gov. Gavin Newsom (D) tweeted late Sunday that he and his family are quarantining after being exposed to COVID-19.

Details: Newsom said they learned Friday that three of his children had come into contact with a California Highway Patrol officer who tested positive for the coronavirus. "Thankfully, the entire family tested negative today," Newsom said.

Operation Warp Speed leader: COVID vaccine push is "isolated from a political environment"

Moncef Slaoui in the Rose Garden on Nov. 13. Photo: Mandel Ngan/AFP via Getty Images

Moncef Slaoui, the White House's top scientific adviser to Operation Warp Speed, told Chuck Todd on "Meet the Press" on Sunday that the Trump administration's efforts to accelerate the development of a coronavirus vaccine is "isolated from a political environment" and that a change in administration "doesn't, frankly, make a difference" on its efficacy.

Why it matters: Slaoui told ABC's George Stephanopoulos on Sunday that he has not yet had contact with Joe Biden's transition team, as the president-elect prepares to inherit one of the country's biggest crises ahead of an expected vaccine distribution effort that would require massive logistical cooperation between states and the federal government.