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The H1N1 virus, responsible for the deadly Spanish Flu outbreak in 1918. Photo: BSIP/UIG Via Getty Images

Another global threat — one that is a repeated refrain amongst the White House, Centers for Disease Control, former national security advisers and even Bill Gates — is a pandemic.

Between the lines: Influenza is of particular concern for health officials, even though there are more contagious viruses — for example, measles — and more deadly ones, like Ebola.

  • But the flu virus can mutate quickly, sometimes acquiring a new ability to infect humans easily, causing concern about its potential to spark a pandemic, which happens when a new strain appears that most have no immunity against.
"The combination of a new deadly strain of flu plus air travel plus the ease with which it can be transmitted to other people. That really is the worst case scenario."
— Lisa Monaco, former White House homeland security adviser, on "Axios on HBO"

One challenge with the flu virus is a virulent strain can emerge quickly and seemingly disappear rapidly, making it difficult to anticipate the virus' course and to develop a vaccine against its possible strains.

  • Funding is being directed into the development of a universal flu vaccine that aims to offer broader immunity against different strains of the virus, but researchers face many obstacles. The National Institutes of Health is testing a vaccine and expects early results next year.
  • Gates and others argue the world needs a multilateral pandemic response program — including a universal vaccine — to mitigate the threat of pandemic flu (and other pathogens).
"We are fooling ourselves if we think that we can do this alone, that it's only about what happens within the borders of our country. It has to be a global health security effort."
— Lisa Monaco

Our thought bubble, per Axios' Eileen Drage O'Reilly: Emerging virulent pathogens are a threat each nation needs to report on a transparent basis to promote possible global coordination to halt their spread.

Go deeper:

Go deeper

Trump can't quit mainstream media

Bob Woodward and Robert Costa are interviewed by Chuck Todd on "Meet the Press" in September. Photo: William B. Plowman/NBC via Getty Images

Bob Woodward and Robert Costa issued a rebuttal on Friday to a statement by former President Donald Trump that misrepresented their reporting — and once again showed the 45th president's thin skin about mainstream media.

Driving the news: "Former President Trump said ... our book, 'Peril,' implied that he was planning to go to war with China," the statement begins. "[W]e report that Chairman of Joint Chiefs Mark Milley 'believed that Trump did not want a war' before or after the 2020 election."

NY declares state of emergency amid concerns over Omicron COVID variant

Governor Kathy Hochul makes an announcement about a new plan transforming Penn Station on Nov. 3, 2021. Photo: Lev Radin/Pacific Press/LightRocket via Getty Images

New York Gov. Kathy Hochul on Friday declared a state of emergency amid rising COVID-19 cases and the newly-identified Omicron variant of the virus.

Driving the news: The declaration enables the state to acquire supplies to fight a potential surge in cases, increase hospital capacity and combat potential staff shortages, NBC's local affiliate reports.

4 hours ago - Health

First cases of COVID-19 Omicron variant discovered in U.K.

People wearing masks walk in London on Nov. 25. Photo: Li Ying/Xinhua via Getty Images

Two cases of the new COVID-19 Omicron variant were detected in the United Kingdom overnight, the U.K. Health Security Agency announced Saturday.

Why it matters: The discovery comes as the world scrambles to respond to concerns over the new variant, discovered in South Africa earlier this week.