New today: House Speaker Paul Ryan won’t run for re-election, a decision whose timing was first reported by Axios’ Jonathan Swan.

By the time Nov. 6 rolls around, there will be at least 56 vacated House seats up for grabs — more than two-thirds of those are held by Republicans this term. The openings are significant because incumbents have outperformed non-incumbents of the same party in similar districts by about seven points in the last decade or so, per the New York Times.