COVID and overdoses drove Colorado's death rate in 2021

• "It is disconcerting to see (death) rates are still this high at the end of 2021," Emily Johnson, the Colorado Health Institute's policy director, told the Denver Post.

By the numbers: The three leading causes of death in 2021 were heart disease, cancer and COVID-19.

• The state recorded 48,284 deaths last year, with an age-adjusted death rate of 784.8 per 100,000 people — a smidge lower than 2020's rate of 785.4.
• 5,298 deaths were caused by the coronavirus, averaging a rate of 82.5 per 100,000 people, compared to 72.8 in 2020.
• 1,943 Coloradans died by overdose — a jump to 32.6 per 100,000 people from 21.6 in 2020.
• Longstanding demographic disparities persist, with Black residents averaging the highest overall death rate despite seeing a 7% improvement between 2020 and 2021.

What to watch: Whether we see a surge in COVID-19 deaths this year may depend on how quickly vaccines are retooled to fight the latest variants, and how quickly people get them (if they even do so).