Iranian Supreme Leader Ayatollah Ali Khamenei. Photo: Iranian Leader's Press Office handout/Anadolu Agency/Getty Images

Iranian foreign ministry spokesman Abbas Mousavi tweeted Tuesday that new U.S. sanctions imposed on the country, including on its Supreme Leader Ayatollah Ali Khamenei, marks the "permanent closure of the path of diplomacy."

What they're saying: "Trump's desperate administration is destroying the established international mechanisms for maintaining world peace and security," Mousavi said in the tweet, translated by Reuters.

The big picture: Escalating tensions with Iran in recent weeks led Trump to authorize and then cancel a military strike on Thursday, calling it a disproportionate response to Iran's downing of an unmanned U.S. drone. The new sanctions form part of the "maximum pressure" campaign that the Trump administration has embarked on following the president's withdrawal from the 2015 Iran nuclear deal.

What he's saying: Trump stressed during an interview with The Hill on Monday he hoped the sanctions could one day be lifted.

This article has been updated with Trump's comments and to give more context.

Go deeper: Timeline: How Trump and Tehran came to the brink of war

Go deeper

Updated 11 mins ago - Politics & Policy

Coronavirus dashboard

Illustration: Sarah Grillo/Axios

  1. Global: Total confirmed cases as of 6 p.m. ET: 32,683,686 — Total deaths: 990,977 — Total recoveries: 22,535,887Map.
  2. U.S.: Total confirmed cases as of 6 p.m. ET: 7,072,897 — Total deaths: 204,446 — Total recoveries: 2,727,335 — Total tests: 99,488,275Map.
  3. States: New York daily cases top 1,000 for first time since June — U.S. reports over 55,000 new coronavirus cases.
  4. Health: The long-term pain of the mental health pandemicFewer than 10% of Americans have coronavirus antibodies.
  5. Business: Millions start new businesses in time of coronavirus.
  6. Education: Summer college enrollment offers a glimpse of COVID-19's effect.

What they're saying: Trump nominates Amy Coney Barrett for Supreme Court

Judge Amy Coney Barrett in the Rose Garden of the White House on Sept. 26. Photo: Oliver Douliery/AFP via Getty Images

Democratic and Republican lawmakers along with other leading political figures reacted to President Trump's Saturday afternoon nomination of federal appeals court Judge Amy Coney Barrett to succeed Justice Ruth Bader Ginsburg on the Supreme Court.

What they're saying: "President Trump could not have made a better decision," Senate Majority Leader Mitch McConnell said in a statement. "Judge Amy Coney Barrett is an exceptionally impressive jurist and an exceedingly well-qualified nominee to the Supreme Court of the United States."

Trump introduces Amy Coney Barrett as nominee to replace Ruth Bader Ginsburg

President Trump announced he's nominating federal appeals court Judge Amy Coney Barrett to succeed Justice Ruth Bader Ginsburg on the Supreme Court.

Why it matters: She could give conservatives a 6-3 majority on the high court, and her nomination sets in motion a scramble among Senate Republicans to confirm her with 38 days before the election. Sen. Mitch McConnell appears to have the votes to confirm Barrett with the current majority.