Jun 18, 2019

With antibiotic resistance growing, WHO promotes monitoring tool

Illustration: Sarah Grillo/Axios

Due to the lack of new antibiotics in the pipeline, current drugs must be better monitored and prescribed before the problem of antimicrobial resistance (AMR) reaches a "Titanic" stage, World Health Organization scientists warned Tuesday as they launch a campaign to promote the use of a monitoring tool, AWaRe.

Why it matters: The growing level of superbugs is a potentially "catastrophic" global threat that could have a yearly death toll of 10 million people by 2050. WHO says using AWaRe would be one tool in promoting its goal that 60% of all antibiotics used come from the "access" category of antibiotics, or what's typically thought of as the first or second line of defense.

The backdrop: WHO's essential medicines list divides antibiotics into 3 categories: "access," "watch," and "reserve" with recommendations for when each category should be used.

But, WHO scientists say too many countries either don't have appropriate access to antibiotics or are using antibiotics incorrectly — including for wrong diagnoses, animal husbandry and even plants — causing an increase in AMR.

  • "We need to keep antibiotics working for everyone," which calls for proper monitoring and management of prescriptions, Mariângela Simão, WHO's assistant director general for access to medicines, said in a press briefing.
  • The scientists pointed to the concerning spread of resistant gram-negative bacteria, including Acinetobacter, E. coli and Klebsiella pneumoniae, which often strike hospital patients with problems like pneumonia, bloodstream infections, sepsis, wound or surgical site infections, and meningitis.
  • Another problem is the huge gap between low- and middle-income countries in access to effective and appropriate antibiotics. Simão says more than 1 million children die due to treatable pneumonia, likely from lack of access to appropriate antibiotics.

The bottom line: If AMR is not halted, "this will probably lead to a halt in modern medicine as we know it today," says Hanan Balkhy, WHO's assistant director general for antimicrobial resistance.

Go deeper:

Go deeper

Coronavirus dashboard

Illustration: Sarah Grillo/Axios

  1. Global: Total confirmed cases as of 7 p.m. ET: 855,007 — Total deaths: 42,032 — Total recoveries: 176,714.
  2. U.S.: Leads the world in confirmed cases. Total confirmed cases as of 7 p.m. ET: 186,265 — Total deaths: 3,810 — Total recoveries: 6,910.
  3. Business updates: Should you pay your rent or mortgage during the coronavirus pandemic? Find out if you are protected under the CARES Act.
  4. Public health updates: More than 400 long-term care facilities across the U.S. report patients with coronavirus — Older adults and people with underlying health conditions are more at risk, new data shows.
  5. Federal government latest: President Trump said the next two weeks would be "very painful" on Tuesday, with projections indicating the virus could kill 100,000–240,000 Americans. The White House and other institutions are observing several models to help prepare for when COVID-19 is expected to peak in the U.S.
  6. U.S.S. Theodore Roosevelt: Captain of nuclear aircraft carrier docked in Guam pleaded with the U.S. Navy for more resources after more than 100 members of his crew tested positive.
  7. What should I do? Answers about the virus from Axios expertsWhat to know about social distancingQ&A: Minimizing your coronavirus risk.
  8. Other resources: CDC on how to avoid the virus, what to do if you get it.

Subscribe to Mike Allen's Axios AM to follow our coronavirus coverage each morning from your inbox.

White House projects 100,000 to 240,000 U.S. coronavirus deaths

President Trump said at a press briefing on Tuesday that the next two weeks in the U.S. will be "very painful" and that he wants "every American to be prepared for the days that lie ahead," before giving way to Deborah Birx to explain the models informing the White House's new guidance on the coronavirus.

Why it matters: It's a somber new tone from the president that comes after his medical advisers showed him data projecting that the virus could kill 100,000–240,000 Americans — even with strict social distancing guidelines in place.

Go deeperArrowUpdated 1 hour ago - Health

Paying rent in a pandemic

Illustration: Aïda Amer/Axios

For many people who've lost jobs or income because of the coronavirus pandemic, tomorrow presents a stressful decision: Do you pay your rent or mortgage?

Why it matters: The new CARES Act that was signed by President Trump on Friday protects homeowners and renters who are suffering from the response to the coronavirus pandemic — but it's not “a one-size-fits-all policy rulebook,” a congressional aide tells Axios.

Go deeperArrow3 hours ago - Health