Amy Klobuchar waves to supporters at a polling location in Manchester. Photo: Scott Eisen/Getty Images

MANCHESTER, N.H. —  After the mess and delays of Iowa, Democrats are looking to tonight's presidential primary for some clarity as to whether Bernie Sanders emerges as a clear front-runner — or whether this remains a crowded field through Super Tuesday.

Why it matters: It's unlikely that Pete Buttigieg pulls off a surprise victory, but if he's a close second to the Vermont senator with the regional advantage, that would be a huge boost for the 38-year-old former mayor of a town around 100,000 whose prospects skyrocketed after his performance in Iowa.

  • And watch for Amy Klobuchar, another moderate in the field and a come-from-behind player, who could have a shot at placing third.
  • Most of the polls closed at 7 pm ET, but the rest will remain open until 8 pm.

Details: If Klobuchar beats Elizabeth Warren and Joe Biden, it would give her campaign a shot of confidence and momentum — and likely dollars — to continue into Nevada. It also could make it that much harder for Warren and Biden's campaigns to make the electability case.

  • Klobuchar's campaign feels good about New Hampshire because of how often she was hitting the airwaves while stuck in D.C. for the Senate impeachment trial. 
  • They've been hosting events around the clock — including a last-minute add at 9:30 pm yesterday — to put her in front of as many voters as possible. 
  • They say they've been spending their money wisely, especially by not hiring huge staff like other campaigns.
  • And they're banking on the political makeup and trends of the state: "Expectations are different here because of the independent voters, and New Hampshire likes to elect women," said one campaign aide. 

You can't walk around New Hampshire without hearing mumbles about whether Biden's campaign is over. He left the state earlier today before polls closed to hustle to South Carolina to protect his firewall of black voters he's relied on, while others have done the same this week through their surrogates and teams on the ground.

  • Biden's team has done what it can — and tonight, they're trying to save face after a disappointing finish in Iowa.

Don't forget: In modern history, candidates don't place worse than second in New Hampshire and still go on to become the nominee.

  • But history has rarely had to account for such a crowded Democratic field.

Go deeper

Pelosi, Schumer demand postmaster general reverse USPS cuts ahead of election

Schumer and Pelosi. Photo: Alex Wong/Getty Images

House Speaker Nancy Pelosi (D-Calif.) and Senate Minority Leader Chuck Schumer sent a letter to Postmaster General Louis DeJoy on Thursday calling for the recent Trump appointee to reverse operational changes to the U.S. Postal Service that "threaten the timely delivery of mail" ahead of the 2020 election.

Why it matters: U.S. mail and election infrastructure are facing a test like no other this November, with a record-breaking number of mail-in ballots expected as Americans attempt to vote in the midst of a pandemic.

2 hours ago - Science

CRISPR co-discoverer on the gene editor's pandemic push

Photo illustration: Aïda Amer/Axios. Photos: Brian Ach/Getty Images for Wired and BSIP/UIG via Getty Images

The coronavirus pandemic is accelerating the development of CRISPR-based tests for detecting disease — and highlighting how gene-editing tools might one day fight pandemics, one of its discoverers, Jennifer Doudna, tells Axios.

Why it matters: Testing shortages and backlogs underscore a need for improved mass testing for COVID-19. Diagnostic tests based on CRISPR — which Doudna and colleagues identified in 2012, ushering in the "CRISPR revolution" in genome editing — are being developed for dengue, Zika and other diseases, but a global pandemic is a proving ground for these tools that hold promise for speed and lower costs.

Updated 2 hours ago - Politics & Policy

Coronavirus dashboard

Illustration: Eniola Odetunde/Axios

  1. Global: Total confirmed cases as of 5 p.m. ET: 18,912,947 — Total deaths: 710,318— Total recoveries — 11,403,473Map.
  2. U.S.: Total confirmed cases as of 5 p.m. ET: 4,867,916 — Total deaths: 159,841 — Total recoveries: 1,577,851 — Total tests: 58,920,975Map.
  3. Politics: Pelosi rips GOP over stimulus negotiations: "Perhaps you mistook them for somebody who gives a damn" — Ohio Gov. Mike DeWine tests positive.
  4. Public health: Majority of Americans say states reopened too quicklyFauci says task force will examine aerosolized spread.
  5. Business: The health care sector imploded in Q2More farmers are declaring bankruptcyJuly's jobs report could be an inflection point for the recovery.
  6. Sports: Where college football's biggest conferences stand on playing.