Fairleigh Dickinson's stunning win against Purdue on Friday makes it the second No. 16 team to ever beat a No. 1 seed — after UMBC's 2018 victory over Virginia (charted above).
Zoom in: An Axios analysis of men's March Madness first-round matchups shows which seeds have pulled off the most upsets since 1985, when the tournament expanded to 64 teams.