Sign up for our daily briefing

Make your busy days simpler with Axios AM/PM. Catch up on what's new and why it matters in just 5 minutes.

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Catch up on the day's biggest business stories

Subscribe to Axios Closer for insights into the day’s business news and trends and why they matter

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Stay on top of the latest market trends

Subscribe to Axios Markets for the latest market trends and economic insights. Sign up for free.

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Sports news worthy of your time

Binge on the stats and stories that drive the sports world with Axios Sports. Sign up for free.

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Tech news worthy of your time

Get our smart take on technology from the Valley and D.C. with Axios Login. Sign up for free.

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Get the inside stories

Get an insider's guide to the new White House with Axios Sneak Peek. Sign up for free.

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Catch up on coronavirus stories and special reports, curated by Mike Allen everyday

Catch up on coronavirus stories and special reports, curated by Mike Allen everyday

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Want a daily digest of the top Denver news?

Get a daily digest of the most important stories affecting your hometown with Axios Denver

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Want a daily digest of the top Des Moines news?

Get a daily digest of the most important stories affecting your hometown with Axios Des Moines

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Want a daily digest of the top Twin Cities news?

Get a daily digest of the most important stories affecting your hometown with Axios Twin Cities

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Want a daily digest of the top Tampa Bay news?

Get a daily digest of the most important stories affecting your hometown with Axios Tampa Bay

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Want a daily digest of the top Charlotte news?

Get a daily digest of the most important stories affecting your hometown with Axios Charlotte

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Want a daily digest of the top Nashville news?

Get a daily digest of the most important stories affecting your hometown with the Axios Nashville newsletter.

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Want a daily digest of the top Columbus news?

Get a daily digest of the most important stories affecting your hometown with the Axios Columbus newsletter.

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Want a daily digest of the top Dallas news?

Get a daily digest of the most important stories affecting your hometown with the Axios Dallas newsletter.

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Sign up for Axios NW Arkansas

Stay up-to-date on the most important and interesting stories affecting NW Arkansas, authored by local reporters

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

The Centers for Disease Control and Prevention says it's using whole genome testing and on-the-ground investigation to try to determine why the current E. coli outbreak from romaine lettuce is more virulent than normal — about half of all people affected have been hospitalized .

Expand chart
Data: Centers for Disease Control; Cartogram: Lazaro Gamio/Axios

What's new: The E. coli outbreak stemming from romaine lettuce grown in Yuma, Ariz., has spread to 19 states and infected at least 84 people, of whom 42 have been hospitalized with 9 suffering from the dangerous hemolytic uremic syndrome, according to a CDC update today.

Threat level: Matthew Wise, deputy branch chief of CDC's Outbreak Response, tells Axios the CDC has confirmed the pathogen is E. coli 157:H7, which is part of the Shiga toxin-producing strain, but they don't know why so many patients need to be hospitalized.

"157:H7 can be a very severe illness, but [50%] is a much higher hospitalization [rate] than we expect," Wise says. "We're doing whole genome sequencing to see if there's anything unique or unusual in this particular strain."

Benjamin Chapman, food safety specialist and associate professor of North Carolina State University, tells Axios that normally the 157:H7 has about a 25%–30% hospitalization rate. He says the higher rate now could be because the strain "picked up genes from other bacteria which cause toxins [in] us," during its normal evolutionary process.

The big question: This episode of E. coli 157:H7 is one of 7 main multistate foodborne outbreaks of E. coli and salmonella that CDC has investigated in 2018. While this appears high compared with 2017 (which had a total of 8 including listeria and cyclospora), it's too early to tell if this is a new trend for the year, Wise and Chapman both say.

  • Chapman says one reason it appears higher is that "we are getting better at connecting the dots, nationally." He says with new safety standards and systems to identify outbreaks, "food is probably safer now than it was for the last 50 years."

Looking ahead: Wise says the CDC is focused on improving via 2 programs:

  1. An increase of funds to the state health departments so they can better track, report and halt outbreaks.
  2. A transition to whole genome sequencing during outbreaks, which should enable officials to see which illness is spreading where. They've completed a similar program for listeria, and the program for salmonella and E. coli should be finished by late 2018–early 2019.

Some challenges facing the CDC:

  • New lack of cultures: Chapman says the state public health system encourages new testing called culture independent diagnostic tests (CIDTs), which can quickly identify pathogen DNA shards but uses up the stool sample that the federal investigators need to be cultured. "It's a challenge," Wise says, because clinicians want the faster CIDT results but "the whole system relies upon the health care facilities to culture the bacteria."
  • IG report: While not directly part of the CDC, the Food and Drug Administration was checked out by the Inspector General's office and its food recall program was found inefficient and ineffective.

Go deeper

Venezuela suspends talks with opposition after Maduro ally extradited to U.S.

Venezuelan President Nicolás Maduro in Caracas, Venezuela, in June. Photo: Gaby Oraa/Bloomberg via Getty Images

A key ally of Venezuela's President Nicolás Maduro was extradited from Cape Verde to the U.S. Saturday to face money laundering charges in Florida, Bloomberg first reported.

Why it matters: Venezuela's government called off negotiations with opposition officials that were scheduled for Sunday in Mexico in response to the extradition of Alex Saab, a Colombian businessman and financial fixer for Maduro, Reuters notes.

3 hours ago - Health

5 times as many police officers have died from COVID as from guns since pandemic began

Photo: Genaro Molina / Los Angeles Times via Getty Images

COVID-19 is the leading cause of death for police officers even though members of law enforcement were among the first to be eligible to receive the vaccine, CNN reports, citing data from the Officer Down Memorial Page.

Why it matters: Nearly 476 police officers have died of COVID-19 since the pandemic started, compared to the 93 deaths as a result of gunfire in the same time period, according to ODMP and CNN.

Virginia energy giant quietly boosts McAuliffe

Former Virginia Gov. Terry McAuliffe speaks during a campaign rally on Oct. 15 in Henrico, Virginia. Photo: Win McNamee/Getty Images

Virginia Democrat Terry McAuliffe has sworn off money from the Richmond company Dominion Energy. But the utility has found more subtle ways to back McAuliffe's gubernatorial bid, records show.

Driving the news: Dominion's political action committee has donated $200,000 to a murky political group called Accountability Virginia PAC, a group with ties to prominent Democrats that's been running ads attacking Republican candidate Glenn Youngkin from the right.