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Neurosurgeon Eddie Chang performing brain surgery. Photo: Barbara Ries/UCSF

Researchers in California announced Wednesday that they have successfully accessed the brain waves of a man unable to speak due to severe paralysis and transformed his thoughts into sentences.

Why it matters: This is the first known "successful demonstration of direct decoding of full words from the brain activity of someone who is paralyzed and cannot speak," neurosurgeon Edward Chang, senior author on the study, said in a statement from the University of California, San Francisco.

"It shows strong promise to restore communication by tapping into the brain's natural speech machinery."
— Chang
  • The study, published in the New England Journal of Medicine on Wednesday, indicates that the approach researchers took could one day help thousands of people who are unable to speak if the method is developed further, according to U.C. San Francisco.

What they did: For the study, known as "BRAVO" (Brain-Computer Interface Restoration of Arm and Voice), researchers worked with a man in his late 30s whose paralysis is due to a brainstem stroke over 15 years ago that left him with limited head, neck, and limb movements. He had been communicating by using a pointer attached to a baseball cap to poke letters on a screen.

  • Chang surgically implanted electrodes into the part of the brain that controls speech. The man worked with researchers to create a 50-word vocabulary — words like "water," "family" and "good" — that Chang's team recognized from brain activity using advanced computer algorithms.
  • Researchers translated signals intended to control muscles of the vocal system for speaking words, rather than signals to move the arm or hand to enable typing.
  • Chang said in his statement that this approach, known as speech neuroprosthesis, tapped into the natural and fluid aspects of speech, promising more rapid and organic communication.

Of note: The study follows an international team of researchers announcing in May that they helped a person with paralysis translate their imagined handwriting into text through a brain–computer interface that was faster than other types of assistive communication.

What they're saying: Leigh Hochberg, a neurologist with Massachusetts General Hospital, Brown University and the Department of Veterans Affairs, who wasn't involved in Chang's study but co-wrote an editorial on it, said this speech neuroprosthesis research was part of a wave of innovative progress in the field, per the New York Times.

  • "It's now only a matter of years before there will be a clinically useful system that will allow for the restoration of communication," added Hochberg, who directs the BrainGate project, which is working on projects to help people affected by neurological disease.

Go deeper

Study: Police killings are mislabeled in federal data by more than 55%

A protester speaks into a bull horn while holding a sign with images of deceased Native American woman Georgianna Jackson during a protest to voice their concerns about police killings. Photo: Ty O'Neil/SOPA Images/LightRocket via Getty Images

More than half of police killings since 1980 have been incorrectly categorized, according to a study from researchers at the University of Washington.

Why it matters: The study indicates that deaths at the hands of police officers have been undercounted, significantly skewering the perception of what the researchers called a public health crisis, the Washington Post reports.

3 hours ago - World

U.S. and NATO answer Putin in writing while bracing for Ukraine invasion

NATO Secretary-General Jens Stoltenberg. Photo: Dursun Aydemir/Anadolu Agency via Getty

The U.S. and NATO provided Russia with written proposals on Wednesday to advance a "diplomatic path forward," even as they warned that Russia could invade Ukraine within days.

Why it matters: This is a delicate diplomatic balancing act. The U.S. and NATO want to show they're serious about diplomacy but unwilling to compromise on "core principles" — all without providing Vladimir Putin with an additional pretext for escalation.

The political leanings of the Supreme Court justices

Data: Martin-Quinn scores; Chart: Axios Visuals

The Supreme Court will continue to have a solid conservative majority even with Justice Stephen Breyer's retirement.

How to read the chart: An analysis by political scientists Andrew Martin and Kevin Quinn, known as the Martin-Quinn Score, places judges on an ideological spectrum. A lower score indicates a more liberal justice, whereas a higher score indicates a more conservative justice.