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President Donald Trump signs a bipartisan bill to stop the flow of opioids into the United States in the Oval Office of the White House on January 10, 2018. Photo: Ron Sachs-Pool via Getty Images

"The Department of Justice and U.S. Drug Enforcement Administration (DEA) have proposed a reduction for controlled substances that may be manufactured in the U.S. next year," according to a forthcoming release provided to Axios.

The details: "Consistent with President Trump’s 'Safe Prescribing Plan' that seeks to 'cut nationwide opioid prescription fills by one-third within three years,' the proposal decreases manufacturing quotas for the six most frequently misused opioids for 2019 by an average ten percent as compared to the 2018 amount."

  • "The Notice of Proposed Rulemaking (NPRM) marks the third straight year of proposed reductions, which help reduce the amount of drugs potentially diverted for trafficking and used to facilitate addiction."
  • "Ultimately, revised limits will encourage vigilance on the part of opioid manufacturers, help DEA respond to the changing drug threat environment, and protect the American people from potential addictive drugs while ensuring that the country has enough opioids for legitimate medical, scientific, research, and industrial needs."

Yes, but: The biggest problem is still synthetic opioids like fentanyl, writes Axios health care editor Sam Baker.

  • Roughly 30,000 people fatally overdosed on synthetic opioids last year — about the same number as heroin and prescription opioids combined. (Some people are counted multiple times because multiple drugs were in their systems when they died.)

Fentanyl’s risks are threefold: It’s easy to make and ship; it’s incredibly potent; and it shows up in different places, at different strengths.

  • That might help explain why overdose deaths are becoming more diverse.
  • “In some places, the type of synthetic drugs mixed into heroin changes often,” the New York Times notes. “The penetration of fentanyl into more heroin markets may explain recent increases in overdose deaths among older, urban black Americans; those who used heroin before the recent changes to the drug supply might be unprepared for the strength of the new mixtures.”

Go deeper

Updated 37 mins ago - Politics & Policy

U.S. sounds alarm on Ukraine

Conscripts line up at a Russian railway station yesterday before departing for Army service. Photo: Sergei Malgavko/TASS via Getty Images

The Biden administration is "deeply concerned" by new intelligence — detailed for Axios and other outlets — showing Russia stepping up preparations to invade Ukraine as soon as early 2022.

Why it matters: Most of this was known from public sources and satellite imagery, but the administration is sending a stronger signal by releasing specific details from the intelligence community.

CNN fires Chris Cuomo

Photo: Kevin Mazur/Getty Images for CNN

CNN said Saturday evening it has fired one of its star anchors, Chris Cuomo, following new revelations from a legal review made by the company into Cuomo's involvement in the management of his brother's sexual harassment scandal.

Why it matters: Saturday's firing speaks to how much pressure CNN was under by employees and critics to address Cuomo's behavior.

Updated 3 hours ago - Energy & Environment

Electric car prices could go up before they come down

Illustration: Eniola Odetunde/Axios

The secret to affordable electric vehicles is cheaper batteries. But after years of falling prices, battery costs are now headed in the wrong direction.

Why it matters: Costlier batteries could drive up the price of electric vehicles — threatening the auto industry's transition away from fossil fuels, and, in turn, society's fight against climate change.

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