Jessica Kourkounis / AP

Drugs approved in recent years that can cure hepatitis C may have severe side effects, including liver failure, according to a new report by the Institute for Safe Medication Practices. The report, which the NYT has analyzed in depth, looks at 9 popular antiviral drugs, including the widely used Sovaldi and Harvoni — both made by Gilead Sciences and priced at $1k per pill. The drugs have been successful for many patients in curing the disease within 12 weeks.

Disclaimer: The number of risks appear relatively low, and the findings are not conclusive. But experts say the report is a warning that shouldn't be ignored. Thomas Moore, an author of the report, said the study reflects a larger question about the drug approval process. Approval for the newer hepatitis C drugs was expedited because better treatments were so badly needed.

Why it matters: Hepatitis C drugs like Sovaldi carry a huge price tag, but they've also been a point of pride for the drug industry — since they can cure a disease that wasn't curable before. That, in their view, was a good justification for the price. But if the drugs cause horrible side effects, it may be harder to make that case.

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The two sides of America's coronavirus response

Illustration: Eniola Odetunde/Axios

America's bungled political and social response to the coronavirus exists side-by-side with a record-breaking push to create a vaccine with U.S. companies and scientists at the center.

Why it matters: America's two-sided response serves as an X-ray of the country itself — still capable of world-beating feats at the high end, but increasingly struggling with what should be the simple business of governing itself.

Joe Biden introduces Kamala Harris in first joint appearance

Joe Biden formally introduced Sen. Kamala Harris as his running mate on Wednesday, telling a socially-distanced gymnasium in Wilmington, Del.: "I have no doubt that I picked the right person to join me as the next vice president of the United States of America."

Why it matters: Harris is a historic pick for vice president, becoming the first Black woman and first South Asian woman to be named to a major-party U.S. presidential ticket. "Kamala knows how to govern," Biden said. "She knows how to make the hard calls. She is ready to do this job on day one."

Updated 1 hour ago - Politics & Policy

Coronavirus dashboard

Illustration: Annelise Capossela/Axios

  1. Global: Total confirmed cases as of 4:30 p.m. ET: 20,439,274 — Total deaths: 744,941— Total recoveries: 12,632,604Map.
  2. U.S.: Total confirmed cases as of 4:30 p.m. ET: 5,180,226 — Total deaths: 165,510 — Total recoveries: 1,714,960 — Total tests: 63,252,257Map.
  3. Politics: Pelosi says Mnuchin called her, White House is "not budging" on stimulus position.
  4. Business: U.S. already feeling effects of ending unemployment benefits.
  5. Public health: America is flying blind on its coronavirus response.
  6. Education: New Jersey governor allows schools to reopenGallup: America's confidence in public school system jumps to highest level since 2004.