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British Prime Minister Boris Johnson's minority government partner, Northern Ireland's Democratic Unionist Party, said in a statement Thursday that it can't back the Brexit deal he's negotiated with the European Union "as things stand."

Why it matters: It's a major blow to Johnson as the DUP's support is vital to his plan to get an agreement approved by the British Parliament. The United Kingdom is due to exit the EU on Oct. 31.

The big picture: Per Axios' Shane Savitsky, a major sticking point in negotiations had been the Irish backstop — which aims to prevent a hard border with customs controls between the EU member country Ireland and Northern Ireland, which is part of the U.K. It's the only land border the EU and U.K. would share.

  • AP reports that negotiators worked into the night Wednesday on regulations concerning customs and value-added tax, which would "regulate trade in goods" at the border.

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Editor's note: This article has been updated with new details throughout.

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Coronavirus dashboard

Illustration: Sarah Grillo/Axios

  1. Politics: Ex-FDA chief: Pence campaigning after COVID exposure puts others at risk — Mark Meadows: "We are not going to control the pandemic"— COVID-19 looms over White House Halloween celebrations.
  2. Health: 13 states set single-day coronavirus case records last week — Fauci says maybe we should mandate masks if people don't wear themU.S. reports over 80,000 new cases for second consecutive day.
  3. World: Italy tightens restrictions Spain declares new state of emergency.

Amy Coney Barrett's immediate impact

Illustration: Eniola Odetunde/Axios

In her first week on the job, Amy Coney Barrett may be deciding which votes to count in the presidential election. By her third week, she’ll be deciding the fate of the Affordable Care Act.

Where it stands: The Senate votes on Barrett’s nomination tomorrow. If she’s confirmed, Chief Justice John Roberts is expected to swear her in at the Supreme Court within hours, an administration official tells Axios.

Texas Democrats beg Biden to spend now

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The Biden campaign is rebuffing persistent pleas from Texas Democrats to spend at least $10 million in the Lone Star state, several people familiar with the talks tell Axios.

Why it matters: If Texas — which has 38 electoral votes and is steadily getting more blue, but hasn't backed a Democrat for president since 1976 — flipped to the Biden column, it would be game over. But the RealClearPolitics polling average stubbornly hovers at +2.6 for Trump — and Team Biden appears more focused on closer targets.