The experimental vaccine against the AIDS virus for the 2016 clinical trial. Photo: Mujahid Safodien/AFP via Getty Images

A vaccine aimed at preventing the human immunodeficiency virus (HIV) has failed and will end its clinical trial in South Africa early, according to the National Institute of Allergy and Infectious Diseases.

Why it matters: About 34 million people are living with HIV/AIDS globally, according to 2018 data from the World Health Organization. South Africa has one of the highest HIV rates in the world, with young women especially at risk.

"An HIV vaccine is essential to end the global pandemic, and we hoped this vaccine candidate would work. Regrettably, it does not. Research continues on other approaches to a safe and effective HIV vaccine, which I still believe can be achieved."
— Anthony Fauci, director of the NIAID, said in a written statement on Monday

Details: The trial, sponsored by NIAID, began in 2016 with 5,407 HIV-negative volunteers across South Africa and was supposed to end in July 2022.

  • 129 HIV infections occurred among the vaccine recipients, and 123 HIV infections occurred among the placebo recipients.
  • There is no evidence that the vaccine caused harm, NIAID said.
  • The Global HIV Vaccine Enterprise expressed "deep disappointment" in learning the trial was ending, according to a statement.

What's next: Two late-stage, multinational HIV vaccine trials are still being conducted by the National Institutes of Health.

Go deeper: HIV-positive babies could benefit from treatment days after birth

Go deeper

"Not enough": Protesters react to no murder charges in Breonna Taylor case

A grand jury on Wednesday indicted Brett Hankison, one of the Louisville police officers who entered Breonna Taylor's home in March, on three counts of wanton endangerment for firing shots blindly into neighboring apartments.

Details: Angering protesters, the grand jury did not indict any of the three officers involved in the botched drug raid on homicide or manslaughter charges related to the death of Taylor.

Two officers shot in Louisville amid Breonna Taylor protests

Police officers stand guard during a protest in Louisville, Kentucky. Photo: Ben Hendren/Anadolu Agency via Getty Images

Louisville Metro Police Department said two officers were shot downtown in the Kentucky city late Wednesday, just hours after a grand jury announced an indictment in the Breonna Taylor case.

Details: A police spokesperson told a press briefing a suspect was in custody and that the injuries of both officers were not life-threatening. One officer was "alert and stable" and the other was undergoing surgery, he said.

Updated 4 hours ago - Politics & Policy

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