Sign up for our daily briefing

Make your busy days simpler with Axios AM/PM. Catch up on what's new and why it matters in just 5 minutes.

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Catch up on coronavirus stories and special reports, curated by Mike Allen everyday

Catch up on coronavirus stories and special reports, curated by Mike Allen everyday

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Denver news in your inbox

Catch up on the most important stories affecting your hometown with Axios Denver

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Des Moines news in your inbox

Catch up on the most important stories affecting your hometown with Axios Des Moines

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Minneapolis-St. Paul news in your inbox

Catch up on the most important stories affecting your hometown with Axios Twin Cities

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Tampa Bay news in your inbox

Catch up on the most important stories affecting your hometown with Axios Tampa Bay

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Charlotte news in your inbox

Catch up on the most important stories affecting your hometown with Axios Charlotte

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Please enter a valid email.

Please enter a valid email.

Subscription failed
Thank you for subscribing!

Photo: Jerry Naunheim Jr./C2N Diagnostics via AP

A non-COVID medical breakthrough: People over 60 now have access to a blood test for Alzheimer's disease.

Why it matters: The existing PET brain scan test costs some people about $5,000 and often isn't covered by insurance, AP reports.

  • Both the blood test and the brain scan are looking for a buildup of a protein called beta-amyloid, which combined with symptoms like memory loss can lead to a dementia diagnosis.
  • The test hasn't received FDA approval, and it's being sold under rules for commercial labs.

The big picture: Roughly 5.5 million Americans may have Alzheimer's-induced dementia, the NIH reports.

  • Earlier diagnoses can't stop the disease, the NIH notes, but treatments can prolong the period before people lose the ability to function on their own.

Between the lines: C2N Diagnostics of St. Louis, which is selling the test and seeking FDA approval, hasn't published any data on the test's accuracy, AP notes.

  • Company promotional materials cite results comparing the test to PET brain scans.
  • If a PET scan showed amyloid buildup, the blood test also gave a high probability of that in 92% of cases and missed 8% of them.
  • If the PET scan was negative, the blood test ruled out amyloid buildup 77% of the time. The other 23% got a positive result. Published research suggests it may detect amyloid buildup before it’s evident on scans.

The other side: Heather Snyder of the Alzheimer’s Association told the AP the organization won’t endorse a test without FDA approval.

The bottom line: “It’s not a cure, it’s not a treatment, but you can’t treat the disease without being able to diagnose it," Alzheimer's researcher Dr. Michael Weiner told the N.Y. Times when the research was first published.

  • "And accurate, low-cost diagnosis is really exciting, so it’s a breakthrough."

Go deeper

Bryan Walsh, author of Future
Dec 16, 2020 - Health

How mass rapid tests could help curb the pandemic

Illustration: Aïda Amer/Axios

Vastly expanded approval and distribution of rapid, at-home tests represents a powerful tool in the fight against COVID-19 — and just possibly, the future of disease diagnostics.

Why it matters: Vaccines will take time to arrest the spread of the coronavirus — even without problems around distribution and acceptance. Some experts believe mass rapid testing could quickly identify who is really at risk of spreading COVID-19 and turn around the out-of-control pandemic in the U.S.

Updated 3 hours ago - World

Over 3,000 detained in protests across Russia demanding Navalny's release

Russian police officers beat protestesters at a rally against of jailing of oppositon leader Alexei Navalny in Moscow on Saturday. Photo: Mikhail Svetlov/Getty Images

Police in Russia on Saturday arrested more than 3,300 people as protesters nationwide demanded that opposition leader Alexey Navalny be released from jail.

Details: Demonstrations began in the eastern regions of Russia and spread west to more than 60 cities.

Updated 5 hours ago - Politics & Policy

Arizona Republicans censure Cindy McCain and GOP governor

Combination images of Cindy McCain and Gov. Doug Ducey. Photo: FilmMagic/FilmMagic for U.S.VETS/Michael Brochstein/SOPA Images/LightRocket via Getty Images

Arizona Republican Party members voted on Saturday to censure prominent GOP figures Cindy McCain, Gov. Doug Ducey and former Sen. Jeff Flake (R-Ariz.), who've all faced clashes with former President Trump.

Why it matters: Although the resolution is symbolic, this move plus the re-election of the Trump-endorsed Kelli Ward as state GOP chair shows the strong hold the former president has on the party in Arizona, despite President Biden winning the state in the 2020 election.