First look: Chamber of Commerce says business is "fed up" with Washington

The polarization, the gridlock, the regulatory overreach, and the inability to act smartly and strategically for our future is making it harder for all of us to do our jobs, fulfill our roles, and move this country forward.

Clark will unveil an "Agenda for American Strength" that includes "bolstering strength" through building, people, energy, global leadership and rule of law.

Go deeper: U.S. Chamber's "State of American Business Data Center" ... Register here for today's 11 a.m. ET event.