Sep 23, 2017

What to watch for with gene therapy

Image: cover of this week's Barron's Magazine

"Gene Therapy Is Nearing a Major Breakthrough: Therapies that replace faulty genes with healthy ones to cure deadly diseases are generating exciting lab results. How to invest in a hot sector," by Barron's Andrew Barry:

"The goal of replacement gene therapy is to replace faulty genes with normal ones, in the hope of producing significant benefits or even cures. The process involves packaging healthy genes into neutered viruses, ... which then act as vectors delivered in a single dose either into the bloodstream or .. where the disease is."

Why it matters: "The first regulatory approval for this technology could come [from the FDA] as soon as January ... Other approvals could follow, igniting even greater interest in the field — and in the shares of several biotech companies making impressive headway in clinical trials."Free link for Axios readers. With graphic, "How replacement gene therapy works."

P.S. "Dow 1,000,000: Warren Buffett predicts that the benchmark will hit that number by 2117." (It closed yesterday at 22,000.) Free link for Axios readers.

Go deeper

John Kelly defends James Mattis against Trump attacks

John Kelly in the White House in July 2017. Photo: Cheriss May/NurPhoto via Getty Images

Former White House chief of staff John Kelly defended James Mattis on Thursday after President Trump attacked the former defense secretary as "the world's most overrated general" and claimed on Twitter that he was fired.

What he's saying: “The president did not fire him. He did not ask for his resignation,” Kelly told the Washington Post in an interview. “The president has clearly forgotten how it actually happened or is confused."

Barr claims "no correlation" between removing protesters and Trump's church photo op

Attorney General Bill Barr said at a press conference Thursday that there was "no correlation" between his decision to order police to forcibly remove protesters from Lafayette Park and President Trump's subsequent visit to St. John's Episcopal Church earlier this week.

Driving the news: Barr was asked to respond to comments from Defense Secretary Mark Esper, who said Tuesday that he "did not know a photo op was happening" and that he does everything he can to "try and stay out of situations that may appear political."

Updates: Cities move to end curfews for George Floyd protests

Text reading "Demilitarize the police" is projected on an army vehicle during a protest over the death of George Floyd in Washington, D.C.. early on Thursday. Photo: Yasin Ozturk/Anadolu Agency via Getty Images

Several cities are ending curfews after the protests over the death of George Floyd and other police-related killings of black people led to fewer arrests and less violence Wednesday night.

The latest: Los Angeles and Washington D.C. are the latest to end nightly curfews. Seattle Mayor Jenny Durkan tweeted Wednesday night that "peaceful protests can continue without a curfew, while San Francisco Mayor London Breed tweeted that the city's curfew would end at 5 a.m. Thursday.