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J. Scott Applewhite / AP

The Senate has officially taken up legislation to repeal the Affordable Care Act — overcoming a hurdle Republicans weren't sure they could clear just a few days ago. Fifty Republican senators voted to start the debate, with Vice President Mike Pence breaking the tie.

How it happened: Sens. Susan Collins and Lisa Murkowski, sitting next to each other in the Senate chamber, voted against the motion, along with all 46 Democrats and two Democrat-leaning independents. Protesters in the galleries shouted "Kill the bill! Don't kill us!" and "Shame!"

The big moment: The standing ovation for Sen. John McCain as he walked in to vote for the motion.

One tense moment: Sen. Ron Johnson, another Republican who has expressed concerns, had a long talk on the floor with Senate Majority Leader Mitch McConnell before casting his vote. He voted yes, right after McCain.

What's next: Twenty hours of debate, followed by votes on the Senate's repeal and replacement plan and a 2015 bill that would repeal much of the ACA without replacing it. If both fail, all votes will be to amend the House-passed health care bill, which is the vehicle they're technically starting with.

We can't rule out other versions of repeal, either. Even McCain, in a floor speech with all of the senators listening, made it clear he wants changes in the Senate bill: "I will not vote for the bill as it is today."

The bottom line: No one knows if any of the repeal proposals can pass the Senate — but it will be harder for Senate Republicans to give up and shelve the effort now that they've gotten this far.

Go deeper

3 hours ago - Sports

Unvaccinated athletes face 21-day quarantine at Beijing Olympics

Logos for the 2022 Winter Olympics at Yanqing Ice Festival in February 2021 in Beijing. Photo: Lintao Zhang/Getty Images)

Athletes, staff members and journalists at the 2022 Beijing Olympic and Paralympic Winter Games who have not been vaccinated against the coronavirus will be required to quarantine for three weeks, the International Olympic Committee (IOC) outlined in its newly-published "playbooks."

Why it matters: The quarantine period is longer than the Games themselves, meaning vaccinations or an earlier arrival date will be required to participate in or cover the Games.

Dan Primack, author of Pro Rata
5 hours ago - Economy & Business

FTX CEO predicts more U.S. crypto flight

Photo: "Axios on HBO"

FTX doesn't look much like a company valued at $25 billion. Its new headquarters, located in a sleepy part of The Bahamas, is so nondescript as to not even have a sign. But it does expect to soon have neighbors.

Driving the news: Founder and CEO Sam Bankman-Fried tells "Axios on HBO" to expect "more and more crypto flight from the states" if the U.S. doesn't soon create a regulatory regime for cryptocurrencies.

Developed countries reveal $100 billion climate finance plan ahead of COP26

Alok Sharma, head of the UN Climate Summit in Glasgow, speaks in Paris on Oct. 12. ( Li Yang/China News Service via Getty Images)

After 12 years of fits and starts, industrialized nations on Monday put forward a detailed plan to provide at least $100 billion annually in climate aid to developing countries starting by 2023.

Why it matters: The plan, presented by representatives of Canada and Germany, is aimed at defusing one of the biggest sources of tension at COP26, which is the failure of industrialized nations to follow through on their financial commitments.

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