The FDA approved a groundbreaking new drug for the most common form of pancreatic cancer, offering patients a more effective treatment against one of the deadliest types of cancer.

💊 The first-of-a-kind pill, called daraxonrasib, blocks a mutated protein that fuels tumor growth in more than 90% of pancreatic cancer cases.

• The daily pill will be sold by Revolution Medicines under the brand name Rasonque.

Patients taking the drug nearly doubled their survival time, with fewer severe side effects, in a study that randomly assigned them to receive the experimental treatment or additional chemotherapy.

• The treatment hit the spotlight earlier this year when former Sen. Ben Sasse (R-Neb.) described his positive experience with it on "60 Minutes."

🩻 Pancreatic cancer is one of the deadliest cancers, in large part because it's often not detected until it's spread.

• The American Cancer Society estimates that about 67,000 new cases will be diagnosed in the U.S. this year, while more than 52,000 people will die from the disease.

Dr. Pashtoon Kasi of City of Hope Orange County, a California-based cancer center, tells AP: "This is not a cure, it's one more option for these patients."

• "But it's the best option we've ever had."

Go deeper.

Share prices for luxury apparel maker Canada Goose are down amid tensions between the U.S. and longtime ally Canada, Axios' Emily Peck reports.

• The company is known for its pricey parkas worn by various A-listers.

📉 Canada Goose stock has been falling all year amid higher tariffs from its southern neighbor.

• The prospect of a warmer winter courtesy of El Niño isn't great for the outerwear business either, Wells Fargo analysts noted this week.

By the numbers: A 50% tariff on Canadian goods — which kicked in this past weekend — would increase Canada Goose's effective tariff rate on U.S. imports from 4.3% to 41.4%, per a Bank of America estimate.

• Go deeper.

1. 🍔 The average American worker earns enough money to buy 10,215 Big Macs yearly, per The Economist's newly updated Big Mac index. It's a long-standing measurement of global purchasing power. Gift link.
2. 💰 Meta agreed to settle with U.S. states for up to $16.7 billion in a landmark lawsuit over allegations that Facebook and Instagram were designed in ways that harm children. The company is calling on peers to sign on, saying the pact won't work unless they jointly line up behind broad reform. Meta agreed to limited under-18 users to two hours per day on Facebook and Instagram, block them from accessing the platforms from midnight to 6 a.m., and limit notifications during school hours. Go deeper.
3. 🕯️ Actor Tim Curry, beloved for his outlandish and eccentric performances in "The Rocky Horror Picture Show," "Clue" and more, died yesterday at 80, his agent and manager said today. N.Y. Times obit.
4. 🏀 The WNBA's Chicago Sky banned ex-NBA player Enes Kanter Freedom from Wintrust Arena following a verbal dispute with the Sky's Natasha Cloud. Kanter Freedom has been antagonistic toward transgender athletes, declaring to be a woman and claiming WNBA eligibility. Cloud is a vocal supporter of transgender people and other marginalized groups. Go deeper.

Massive flash floods in a border area of Nepal and China killed at least 98 people and left hundreds missing. Get the latest.

Famous sports photographer Jean Fruth recently gave some first-hand baseball photography tips to Axios San Diego's Claire Trageser.

• Fruth has shot games at every MLB park, and co-founded the nonprofit Grassroots Baseball.

⚾️ Fruth tells Axios that when she shows up to photograph a game, she's looking for stories.

• She starts at batting practice with small details, like a glove, bat, ball or a player's hand.

"Then, of course, the game begins, and we have game action and reaction."

• "So game action, a home run, or a play at second. Now who's reacting? Maybe it's the player who created the action celebrating, maybe it's the opposing team, or maybe it's the fans."

Go deeper ... Subscribe to Axios Local.