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Illustration: Sarah Grillo/Axios

As gene-altering technologies become more accessible, there's also a growing risk that they'll be dangerously misused or abused.

Why it matters: "You're talking about manipulating DNA to create a designer pathogen. That’s a terrorist threat," former FDA Commissioner Scott Gottlieb told me.

The big picture: Ethical questions about CRISPR, the gene editing tool, are as old as the technology itself, and they intensified last year with the news of the first gene-edited babies in China.

  • These questions have been further complicated by the fact that genetic alteration technologies are now relatively cheap and easy to use.
  • “These threats have been on people’s mind and on the horizon for a long time. I think now they’re just becoming more manifest because costs are coming down, the technology is more manageable — you don’t have to be as sophisticated to deploy it," Gottlieb said.

Driving the news: NPR reported last week that as synthetic DNA gets cheaper and easier to make, there's growing concern about the technology being used to create bioweapons or dangerous viruses.

  • Josiah Zayner, a "biohacker" who became notorious for using CRISPR on himself in 2017, runs The ODIN, a company that sells DIY gene-editing kits online and teaches people how to use CRISPR. The kits are available on Amazon.
  • California passed a law this summer that outlaws the sale of DIY genetic engineering kits unless they come with explicit warnings that they're not to be used for self-administration, Vox reports.

At the same time, scientific advances in genetics have made breakthrough therapies possible.

  • Only 3 weeks ago, Chinese researchers used CRISPR technology to safely treat a man with cancer and HIV, Bloomberg reported.
  • Legitimate drug development comes with its own complicated ethical questions. Patients and parents of children with life-threatening diseases are likely to start asking for experimental gene therapies, STAT reported last week.

Gene testing — as opposed to gene altering — poses new risks, as well.

  • When consumer DNA testing databases began being used by law enforcement to crack criminal cases, privacy questions arose. And privacy issues have been amplified as medical and sperm donors have lost their assurance of anonymity.
  • DNA testing has also opened the door to creative forms of fraud. Just last week, federal agents took down an alleged Medicare fraud scheme in which seniors were convinced to get their cheeks swabbed for unnecessary DNA tests, as STAT reports.

Go deeper: The ethical red flags of genetically edited babies

Go deeper

19 mins ago - World

Biden to warn Putin U.S. will add troops in Eastern Europe if Russia invades Ukraine

Putin meets Biden in Geneva. Photo: Peter Klaunzer - Pool/Keystone via Getty

President Biden will warn Russian President Vladimir Putin when they speak on Tuesday that if Russia invades Ukraine, the U.S. is prepared to increase its troop presence, capabilities and military exercises on NATO's "eastern flank," a senior administration official told reporters.

Why it matters: The administration believes it's increasingly likely that Putin will order an invasion.

51 mins ago - World

U.S. announces diplomatic boycott of Beijing Winter Olympics

An Olympic-themed sculpture in Beijing on Dec. 1. Photo: Hou Yu/China News Service via Getty Images

The U.S. announced Monday that it will not send officials to the 2022 Beijing Winter Olympics in protest of human rights abuses committed by the Chinese Communist Party.

Why it matters: The diplomatic boycott — which won't prevent American athletes from competing — marks a major escalation between the U.S. and China amid already heightened tensions over the CCP's treatment of Muslim minorities, military threats to Taiwan and economic tariffs.

Stuck jet stream brings blowtorch December in Lower 48, frigid Alaska

Short-term climate outlook for Dec. 13-19, 2021, from the Climate Prediction Center at NOAA. (NOAA/CPC)

The Lower 48 states have seen record-shattering warmth so far this December, with temperatures running as high as 35°F above average for this time of year. The warmth has been so pronounced that during the weekend, brush fires broke out in a snowless, unusually mild Denver metro area.

The big picture: The jet stream, which is a river of air that rides at about 30,000 feet along the temperature contrast between air masses, steering storms as it goes, has been stuck in a position well north of the continental U.S., keeping storms and cold weather at bay.