Illustration: Sarah Grillo/Axios Visuals

MIT Technology Review released excerpts of Chinese scientist He Jiankui's unpublished research on Tuesday, underscoring massive ethical and practical oversights in his claim that he successfully used the gene-editing tool CRISPR to create genetically engineered children.

The bottom line: A primary goal of the experiment was to test if cells could be gene-edited to become HIV resistant. This could have been done without creating human test subjects, MIT notes.

What else they found: The researchers never checked to see if their newly created mutations actually led to HIV resistance — and the experiment itself did not have "clear, immediate medical benefits" for the children or their parents, per MIT.

  • The twin girls could have health issues from different cells in their embryos potentially being edited differently, or from being "mosaic."
  • The research plan was not registered with the China Clinical Trial Registry until after the twins were born — and it only briefly discusses ethics at all.
  • Author and lead researcher He Jiankui thanked John Zhang, head of one of the largest fertility centers in the U.S., for his contributions to the report.

What they didn't find: He's unpublished research, reviewed by MIT, did not disclose the financial interests of the authors or who funded the project. The manuscripts also did not include details on each author’s scientific contribution.

Go deeper: Report: Location of Chinese scientist who says he created first gene-edited babies unknown

Go deeper

Trump signs bill to prevent government shutdown

Senate Majority Leader Mitch McConnel and President Trump arrives at the U.S. Capitol in March. Photo: Samuel Corum/Getty Images

President Trump signed a bill to extend current levels of government funding into the new fiscal year, White House spokesperson Judd Deere confirmed early Thursday.

Driving the news: The Senate on Tuesday passed the legislation to fund the federal government through Dec. 11, by a vote of 84-10.

Editor's note: This is a developing news story. Please check back for updates.

Updated 25 mins ago - Science

In photos: Deadly wildfires devastate California's wine country

The Shady Fire ravages a home as it approaches Santa Rosa in Napa County, California, on Sept. 28. The blaze is part of the massive Glass Fire Complex, which has razed over 51,620 acres at 2% containment. Photo: Samuel Corum/Agence France-Presse/AFP via Getty Images

More than 1700 firefighters are battling 26 major blazes across California, including in the heart of the wine country, where one mega-blaze claimed the lives of three people and forced thousands of others to evacuate this week.

The big picture: More than 8,100 wildfires have burned across a record 39 million-plus acres, killing 29 people and razing almost 7,900 structures in California this year, per Cal Fire. Just like the deadly blazes of 2017, the wine country has become a wildfires epicenter. Gov. Gavin Newsom has declared a state of emergency in Napa, Sonoma, and Shasta counties.

Updated 1 hour ago - Politics & Policy

Coronavirus dashboard

Illustration: Sarah Grillo/Axios

  1. Global: Total confirmed cases as of 12:30 a.m. ET: 33,880,896 — Total deaths: 1,012,964 — Total recoveries: 23,551,663Map.
  2. U.S.: Total confirmed cases as of 12:30 a.m. ET: 7,232,823 — Total deaths: 206,887 — Total recoveries: 2,840,688 — Total tests: 103,939,667Map.
  3. Education: School-aged children now make up 10% of all U.S COVID-19 cases.
  4. Health: Moderna says its coronavirus vaccine won't be ready until 2021
  5. Travel: CDC: 3,689 COVID-19 or coronavirus-like cases found on cruise ships in U.S. waters — Airlines begin mass layoffs while clinging to hope for federal aid
  6. Business: Real-time data show economy's rebound slowing but still going.
  7. Sports: Steelers-Titans NFL game delayed after coronavirus outbreak.