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Bottle of Vicodin pills. Photo: Smith Collection/Gado/Getty Images

The Food and Drug Administration on Friday approved a higher dose of naloxone hydrochloride nasal spray to reverse the effects of opioid overdoses.

The big picture: "Experts and patient advocates say the more potent medicine is needed because low-dose naloxone sprays and injections sometimes must be given multiple times to keep someone alive until medical help arrives," AP writes.

Details: The FDA approved Hikma Pharmaceuticals’ Kloxxad0, which has 8 milligrams of nalox0ne. The highest dose available on the market now is 4 milligrams.

  • "If naloxone is administered quickly, it can counter the opioid overdose effects, usually within minutes. A higher dose of naloxone provides an additional option in the treatment of opioid overdoses," the FDA said.
  • Kloxxado will be sold over-the-counter in packages with two nasal spray devices.
  • Naloxone is a safe medicine and side effects are rare, per the National Institute on Drug Abuse.

What they're saying: "Today’s action meets another critical need in combatting opioid overdose," Patrizia Cavazzoni, director of the FDA’s Center for Drug Evaluation and Research, said in a statement.

  • "Addressing the opioid crisis is a top priority for the FDA, and we will continue our efforts to increase access to naloxone and place this important medicine in the hands of those who need it most."

By the numbers: More than 70,000 people died from opioid overdoses in 2019 and 40% of deaths involve prescription opioids, according to the Department of Health and Human Services.

Go deeper

29 mins ago - Health

Biden reaches agreements with Uber and Lyft to give free rides to vaccine sites

A coronavirus vaccination site in Miami on May 10. Photo: Joe Raedle/Getty Images

The Biden administration has reached agreements with ride-sharing companies Uber and Lyft to offer free rides to coronavirus vaccination sites through July 4, the White House announced Tuesday.

Why it matters: The free rides, starting in the next two weeks, are part of the Biden administration's push to administer at least one vaccine dose to 70% of U.S. adults by Independence Day.

Ben Geman, author of Generate
39 mins ago - Energy & Environment

Biden officials green-light nation's first big offshore wind project

Illustration: Aïda Amer/Axios. Photo by Brendan Smialowski/AFP via Getty Images

The Biden administration today gave final approval to Vineyard Wind, a project off the Massachusetts coast slated to be the country's first large-scale offshore wind farm.

Why it matters: While the green-light for the long-proposed projected was expected, it marks a key step in White House plans to help spur development of a suite of coastal projects off New York, New Jersey and other states.

Global temperatures are cooler in 2021 than other recent years

Data: NASA; Chart: Andrew Witherspoon/Axios

With a moderate La Niña event in the tropical Pacific Ocean, global temperatures in 2021 are running decidedly cooler when compared to recent years.

Why it matters: The lack of a new warmest year record in 2021 could sap some of the sense of urgency among policymakers in the U.S. and abroad during a critical year for enacting stricter emissions cuts to meet the Paris Agreement's targets.