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The U.S. is unlikely to face a fourth wave of the coronavirus, but will likely see plateauing case numbers before they continue to decline, Former FDA commissioner Scott Gottlieb told ABC's "Face the Nation" on Sunday.

Why it matters: It comes amid growing concerns about a possible surge in the U.S. Gottlieb noted that there are still many unanswered questions about new COVID-19 variants that could pose problems down the road.

What they're saying: Gottlieb said a plateau in case numbers could be fueled by the spread of new variants — like the B. 1.526 variant from New York, the South African variant, B.1.351, and the U.K. variant, B.1.1.7 — as well as the easing of safety restrictions.

  • "I don't think we're going to have a fourth wave, I think what we're seeing around the country is parts of the country that are plateauing, and we're seeing upticks in certain parts of the country."
  • "I think what you could see is a plateauing for a period of time before we continue on a downward decline, in large part because B.1.1.7 is becoming more prevalent, in large part because we're pulling back too quickly with respect to taking off our masks and lifting the mitigation."

But, but, but: Gottlieb said questions remain about the variants themselves.

  • "What we don't understand with 1.526 is whether or not people are being reinfected with it and whether or not people who might have been vaccinated are now getting infected with it."
  • "One of the concerns about this particular variant is that it has that mutation that's also in the South African variant, in the B.1.351 variant, that we know in certain cases is causing people who have already had coronavirus to get reinfected with it."

The big picture: Gottlieb said the U.S. must begin more carefully tracking variant cases of COVID-19.

  • "We need to step in much more aggressively and start sequencing cases, especially people who report that they either were previously vaccinated or already had COVID."

Go deeper

Updated 41 mins ago - Health

NIAID: AstraZeneca "may have included outdated information" on COVID vaccine

A healthcare worker holds a vial of AstraZeneca's COVID-19 vaccine at the Pentland Medical Practice in Currie, Scotland, in January. Photo: Russell Cheyne - WPA Pool/Getty Images

NIAID said early Tuesday it's "concerned" that AstraZeneca "may have included outdated information" from a trial of its COVID-19 vaccine that "may have provided an incomplete view of the efficacy data."

Why it matters: The statement comes after the company announced the vaccine it developed with the University of Oxford was found to be 79% effective at preventing symptomatic COVID-19 and 100% effective against severe disease and hospitalization in a Phase III trial.

Updated 1 hour ago - World

In photos: Millions under severe weather warnings amid Australia floods

State Emergency Service workers on their rescue craft on the flooded Hawkesbury River in Richmond, in the Australian state of New South Wales, on March 23. Photo: Mark Kolbe/Getty Images

Heavy rains and flooding pummeling Australia's east coast that have forced thousands to evacuate are set to continue for at least another day, forecasters warn.

The big picture: Rains have lashed New South Wales and southeast Queensland since last Thursday. Prime Minister Scott Morrison told reporters 18,000 people were under evacuation orders and the situation remained "dynamic," with western Sydney the area of "greatest concern." A natural disaster was declared in 16 areas.

Officer among 10 killed in Boulder grocery store shooting

King Sooper's grocery store in Boulder on Monday. Photo: Chet Strange/Getty Images

10 people were killed in a shooting at a grocery store in Boulder, Colorado, on Monday, including one police officer, the local police department confirmed.

What we know: A suspect was in custody and being treated for injuries, Cmdr. Kerry Yamaguchi said. The slain officer was Eric Talley, 51, who was first on the scene and had been with the Boulder Police Department since 2010, said police Chief Maris Herold, who described him as ""heroic."