Mar 28, 2019

EpiPen's evolving market share

Adapted from Leerink Partners and IQVIA; Chart: Andrew Witherspoon/Axios

Brand-name EpiPen barely has any share of the epinephrine injection market these days — a swift change from 2015, when EpiPens controlled 89% of the market and Mylan earned congressional scrutiny for jacking up prices.

Yes, but: Mylan still owns the market through its "authorized" generic, which launched in 2016. That product is exactly the same as EpiPen, except for the label and its smaller price tag, and it has prevented other competing generics from gaining ground.

Where it stands: The price for a pack of Mylan's generic EpiPens is $300, or about half the price of regular EpiPen.

  • Mylan offers large rebates to insurance middlemen so they will cover brand-name EpiPen, but Mylan doesn't have to do that for its generic.
  • People who rely on epinephrine injectors save money on their out-of-pocket costs with the lower-priced generic, and Mylan has been able to keep a loyal following despite its pricing practices.
  • But the net amount everyone collectively spends on the drug hasn't really changed, and the generic EpiPen may be more profitable for Mylan.

What we're watching: Eli Lilly is mirroring Mylan's EpiPen strategy with its most popular insulin.

The bottom line: Drug companies can retain most or all of their turf by competing with themselves through their own generics.

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Mass shooting in Milwaukee: What we know so far

Milwaukee Mayor Tom Barrett in 2012. Photo: John Gress/Corbis via Getty Images

Six people died in a shooting at the Milwaukee Molson Coors brewery complex on Wednesday, including the shooter, Mayor Tom Barrett told reporters at an evening press conference with local police.

What's happening: Police said "there is no active threat" just before 6 pm ET, but noted the scene remains active. Police chief Alfonso Morales told reporters that officers have "more than 20 buildings we have to secure" at the complex and they do not currently have all employees accounted for, as more than 1,000 were at the complex during the shooting.

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Live updates: CDC confirms possible community spread of coronavirus

Data: The Center for Systems Science and Engineering at Johns Hopkins, the CDC, and China's Health Ministry. Note: China numbers are for the mainland only and U.S. numbers include repatriated citizens.

U.S. clinicians have found the novel coronavirus in a person who did not recently return from a foreign country nor have contact with a confirmed case, the CDC said Tuesday.

The big picture: COVID-19 has killed more than 2,700 people and infected over 81,000 others. By Wednesday morning, South Korea had the most cases outside China, with 1,261 infections. Europe's biggest outbreak is in Italy, where 374 cases have been confirmed.

Go deeperArrowUpdated 42 mins ago - Health

Trump assigns Pence to lead U.S. coronavirus response


President Trump announced at a press briefing Wednesday evening that he'll be putting Vice President Mike Pence in charge of leading the administration's response to the coronavirus.

The big picture: In the wake of a market sell-off and warnings from health officials that there's a real threat of the coronavirus spreading in the U.S., Trump sought to reassure the nation and Wall Street that the U.S. is "ready" for whatever comes next.

Go deeperArrowUpdated 2 hours ago - Politics & Policy