Moderna has developed the first experimental coronavirus vaccine, but an approved treatment is more than a year away. Photo: David L. Ryan/The Boston Globe via Getty Images

A healthy U.S. volunteer received the first dose of an experimental coronavirus vaccine, a potential defense against the virus if it becomes a long-term threat.

Where it stands: The trial will ultimately give 45 volunteers two doses about 28 days apart in order to test the vaccine's effectiveness in protecting the subjects against COVID-19. If successful, several more trials with larger subject groups will be needed to prove whether there are common side effects.

Context: The vaccine candidate, code-named mRNA-1273, was developed by the National Institutes of Health and Massachusetts-based biotechnology company Moderna Inc.

  • Several other vaccines from researchers and companies around the world are in development.

What to watch: Even if the trial is successful, a vaccine for mass production and distribution worldwide will likely not be available for 12–18 months, said Anthony Fauci, director of the NIH's National Institute of Allergy and Infectious Diseases.

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Coronavirus dashboard

Illustration: Sarah Grillo/Axios

  1. Global: Total confirmed cases as of 11 a.m. ET: 31,937,244 — Total deaths: 977,624 — Total recoveries: 22,013,874Map.
  2. U.S.: Total confirmed cases as of 11 a.m ET: 6,937,145 — Total deaths: 201,959 — Total recoveries: 2,670,256 — Total tests: 97,459,742Map.
  3. Health: The coronavirus is surging again — Johnson & Johnson begins large phase 3 trial — The FDA plans to toughen standards.
  4. Media: Pandemic spurs journalists to go it alone via email.
  5. Technology: The tech solutions of 2020 may be sapping our resolve to beat the coronavirus
  6. Sports: Here's what college basketball will look like this season.
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Republicans condemn Trump's refusal to commit to peaceful transfer of power

Photo: Joshua Roberts/Getty Images

A number of prominent Republican lawmakers addressed President Trump's refusal on Wednesday to commit to a peaceful transfer of power if he loses November's presidential election.

Driving the news: Senate Majority Leader Mitch McConnell tweeted, "The winner of the November 3rd election will be inaugurated on January 20th. There will be an orderly transition just as there has been every four years since 1792."

2 hours ago - Technology

Pandemic spurs journalists to go it alone via email

Illustration: Aïda Amer/Axios

A slew of high-profile journalists have recently announced they are leaving newsrooms to launch their own, independent brands, mostly via email newsletters.

Context: Many of those writers, working with new technology companies like Substack, TinyLetter, Lede, or Ghost, have made the transition amid the pandemic.

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