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Biogen has been an active stock. Photo: John Tlumacki/The Boston Globe via Getty Images

A lot of Biogen's value hinges on whether federal scientists and regulators will approve or reject its drug candidate for Alzheimer's.

Driving the news: The drug, called aducanumab, has attracted people like Warren Buffett to invest in Biogen's stock on the assumption the drug will score approval for a patient population that desperately seeks a treatment. But other wealthy investors, like Ray Dalio, have taken a less sanguine view and dumped Biogen completely.

By the numbers: Warren Buffett's Berkshire Hathaway hadn't owned any shares of Biogen until it bought 648,000 new shares in the last quarter of 2019, according to regulatory documents flagged by Meg Tirrell of CNBC.

Yes, but: Ray Dalio of Bridgewater Associates sold off all of its 237,000 Biogen shares, according to regulatory filings.

  • Parnassus Investments and HealthCor Management likewise divested all of their Biogen stakes, while a handful of others significantly dialed back investments.

The big picture: The FDA is expected to review and rule on Biogen's application at some point this year. The recent stock trading around Biogen gives a glimpse at how much is riding on this drug, and how much uncertainty there is around approval.

Go deeper: Why there's skepticism around Biogen's Alzheimer's drug

Go deeper

Woman who allegedly stole laptop from Pelosi's office to sell to Russia is arrested

Photo: FBI

A woman accused of breaching the Capitol and planning to sell to Russia a laptop or hard drive she allegedly stole from Speaker Nancy Pelosi's office was arrested in Pennsylvania's Middle District Monday, the Department of Justice said.

Driving the news: Riley June Williams, 22, is charged with illegally entering the Capitol as well as violent entry and disorderly conduct. She has not been charged over the laptop allegation and the case remains under investigation, per the DOJ.

Biden will reverse Trump's attempt to lift COVID-related travel restrictions

Photo: Tasos Katopodis via Getty

The incoming Biden administration will reverse President Trump's last-minute order to lift COVID-19 related travel restrictions, Jen Psaki, the incoming White House press secretary, tweeted.

Why it matters: President Trump ordered entry bans lifted for travelers from the U.K., Ireland, Brazil and much of Europe to go into effect Jan. 26, but the Biden administration will "strengthen public health measures around international travel in order to further mitigate the spread of COVID-19," Jen Psaki said. Biden will be inaugurated on Wednesday, Jan. 20 and Trump will no longer be president by the time the order is set to go into effect.

Dominion sends cease and desist letter to My Pillow CEO Mike Lindell

Photo: Stephen Maturen/Getty Images

Dominion Voting Systems on Monday sent a cease and desist letter to My Pillow CEO Mike Lindell over his spread of misinformation related to the 2020 election.

Why it matters: Trump and several of his allies have pushed false conspiracy theories about the company, leading Dominion to take legal action. It's suing pro-Trump lawyer Sidney Powell for defamation and $1.3 billion in damages, and a Dominion employee has sued Trump himself, OANN and Newsmax.

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