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Illustration: Sarah Grillo/Axios

Shrinking investment and a lack of innovation in the development of new antibiotics is "undermining efforts to combat drug-resistant infections," the World Health Organization warned on Friday, citing two of its new reports.

Why it matters: "Without government intervention, the United Nations estimates that resistant infections could kill 10 million people annually by 2050 and prompt an economic slowdown to rival the global financial crisis of 2008," the New York Times reports.

What's happening: It can take up to 10 years and north of $2 billion to develop a new antibiotic and commercialize it, the Times writes. Large pharmaceutical companies aren't producing as many antibiotics, and of those that are being developed, only a handful target the most dangerous drug-resistant infections.

  • Drug company executives, public health experts and patient advocates are insisting that Washington establish new programs and policies to attract the necessary funding to help struggling antibiotic companies and continue to attract drug company giants.
“Never has the threat of antimicrobial resistance been more immediate and the need for solutions more urgent. Numerous initiatives are underway to reduce resistance, but we also need countries and the pharmaceutical industry to step up and contribute with sustainable funding and innovative new medicines.”
WHO's Director-General, Tedros Adhanom Ghebreyesus

Between the lines: "Unlike drugs that treat chronic conditions and are taken for years, antibiotics save lives, but are taken for just a week or two, diminishing their profitability for drugmakers," the NYT's Andrew Jacobs writes.

The other side: In WHO's report on possible novel therapies, 252 agents in development were identified to target 12 pathogens declared serious threats to humanity, including E. coli, salmonella and the bacteria that can cause gonorrhea.

Yes, but: Among 50 new antibiotics in clinical trials, only two are active against the most worrisome category of bugs, per the Times.

Go deeper: U.S. pushes global effort to fight antibiotic resistance at UN meeting

Go deeper

Jan. 6 select committee subpoenas four Trump aides

Photo: Alex Wong/Getty Images

The Jan 6. select committee investigating the deadly Capitol riot has subpoenaed four aides to former President Trump for testimony and documents.

Why it matters: Former White House chief of staff Mark Meadows, former communications official Dan Scavino, former Defense Department official Kash Patel, and former Trump advisor Steve Bannon were all in touch "with the White House on or in the days leading up to the January 6th insurrection," the committee said in a release.

U.S. friends in Latin America are turning to China

Illustration: Shoshana Gordon/Axios

The U.S. is losing Latin America to China without putting up a fight, Ecuador’s ambassador to Washington told Axios, laying bare her frustrations with early inattention from the Biden administration.

Why it matters: Ecuador isn't alone. China has deepened its engagement in the region, and it's now the top trading partner for many of the region's largest economies. That gives Beijing considerable leverage in a region historically dominated by the U.S., and makes Latin America a major frontier in the global competition for influence.

1 dead, 14 injured in shooting at Kroger grocery store near Memphis

One person was killed and 14 others were injured Thursday in a shooting at a Kroger grocery store in Collierville, Tenn., near Memphis, the town's spokesperson Jennifer Casey said, per CNN.

What they're saying: "I've been involved in [police work] for 34 years and I have never seen anything like [this]," Police Chief Dale Lane said at a press conference.