Members of a medical team monitor simulated patients infected with Ebola. Photo: Paul J. Richards/AFP/Getty Images

The next global plague is coming, Ed Yong writes in the Atlantic, and the U.S. is "disturbingly vulnerable."

The big picture: The total number of outbreaks every 10 years "has more than tripled since the 1980s," Yong says. Bill Gates told Yong that if there was a severe flu pandemic, more than 33 million people could be killed across the world in 250 days.

"Boy, do we not have our act together."
— Bill Gates
The possibilities
  • With 7.6 billion people in the world, and more than half of them living in cities, the chance for an epidemic to spread is increasingly high.
  • Yong writes: "In these dense throngs, pathogens can more easily spread and more quickly evolve resistance to drugs."
The concerns

Treating a plague is expensive: Per Yong, treating three Ebola patients in the U.S. in 2014 cost more than $1 million.

  • A severe flu pandemic would cost an estimated $683 billion, and "global output would fall by almost 5 percent—totaling some $4 trillion."

It takes time, which people don't always have: In 2009, it took four months before vaccines could begin to be rolled out to treat the new pandemic strain of the flu.

  • "By then the disaster was already near its peak. Those doses prevented no more than 500 deaths...Some 12,500 Americans died," Yong writes.

It requires a coordinated federal response, which Yong says "is harder than one might think."

  • In 2016, when President Obama asked Congress for $1.9 billion to fight the Zika virus, "Congress devolved into partisan squabbling," and it took more than seven months to come up with the money ($1.1 billion).
The optimism
  • The Coalition for Epidemic Preparedness Innovations was created last year, and governments and nonprofits have already pledged $630 million. It's focusing on specific illnesses, and pushing towards testing vaccines and stockpiling them.
  • The coalition is also working towards "platform technologies" that would be able to create a vaccine for any kind of virus within 16 weeks of its discovery, Yong writes.
The bottom line

Preparing and confronting a pandemic relies on multiple moving parts, from the doctors to the nurses, appropriate hospital isolation for infected patients, vaccine delivery, Congress appropriation, and more. The director of the National Institute of Allergy and Infectious Diseases, Anthony Fauci, told Yong: "It's like a chain—one weak link and the whole thing falls apart. You need no weak links."

Go deeper

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Data: Business Roundtable; Chart: Naema Ahmed/Axios

A closely-watched CEO economic confidence index rose for the first time after declining for nine straight quarters, according to a survey of 150 chief executives of the biggest U.S. companies by trade group Business Roundtable.

Why it matters: The index, which still remains at a decade low, reflects corporate America's expectations for sales, hiring and spending — which plummeted amid uncertainty when the pandemic hit.

Official says White House political appointees "commandeered" Bolton book review

John Bolton's book "The Room Where it Happened." Photo: Chris Delmas/AFP via Getty Images

A former career official at the National Security Council claims her pre-publication review of former national security adviser John Bolton's explosive book on President Trump was "commandeered by political appointees for a seemingly political purpose," according to a letter from her lawyers filed in court on Tuesday.

Why it matters: The White House fought against the publication of Bolton's book for most of the year on the grounds that it contained harmful and "significant amounts of classified information."

House Democrats unveil sweeping reforms package to curtail presidential abuses

House Speaker Nancy Pelosi. Photo by Stefani Reynolds/Getty Images

House Democrats on Wednesday unveiled sweeping legislation aimed at preventing presidential abuse and corruption, strengthening transparency and accountability, and protecting elections from foreign interference.

Why it matters: While the bill has practically no chance of becoming law while Trump is in office and Republicans hold the Senate, it's a pre-election message from Democrats on how they plan to govern should Trump lose in November. It also gives Democratic members an anti-corruption platform to run on in the weeks before the election.

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