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Data: Company filings; Chart: Naema Ahmed/Axios

Global sales of Humira, the blockbuster drug that treats autoimmune diseases like arthritis and psoriasis, hit $19.9 billion in 2018, an 8.2% increase from 2017, AbbVie reported Friday. AbbVie has collected more than $115 billion in global Humira sales since 2010, 58% of which has come from the U.S.

The bottom line: AbbVie has made and will continue to make a lot of money from Humira. But cheaper copycat versions in Europe are expected to erode sales by $2 billion this year, which sent AbbVie's stock reeling.

By the numbers: A 2-pen box of Humira in the U.S. now retails for almost $5,200, following AbbVie's 6.2% price increase on the medicine. Rebates for Humira average around 40%, so that means U.S. patients who are on typical doses are paying more than $40,000 per year for Humira — the approximate cost of a Ford F-150 pickup truck and a little less than a Tesla Model 3.

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Updated 5 mins ago - Politics & Policy

Ruth Bader Ginsburg will lie in state in Capitol's National Statuary Hall

Photo: Getty Images

House Speaker Nancy Pelosi announced Monday that the late Supreme Court Justice Ruth Bader Ginsburg will lie in state in the Capitol's National Statuary Hall on Friday, making Ginsburg the first woman to ever receive the honor.

The state of play: The Supreme Court also announced Monday that Ginsburg will lie in repose on the front steps of the building on Wednesday and Thursday, allowing the public to pay respects to the late justice outside.

17 mins ago - World

Trump announces new Iran sanctions in effort to maintain international arms embargo

Photo: Anna Moneymaker-Pool/Getty Images

President Trump signed an executive order on Monday that would impose sanctions on any person or entity that contributes to the supply, sale, or transfer of conventional arms to or from Iran or is engaged in providing training and financial support related to those weapons.

Why it matters: The executive order is the first step by the Trump administration to put teeth into its claim that international sanctions on Iran were restored over the weekend, one month after the U.S. initiated the "snapback" process under a United Nations Security Council resolution.

Exclusive: Conservative group launches $2M Supreme Court ad

Screengrab of ad, courtesy of Judicial Crisis Network.

The Judicial Crisis Network is launching a $2.2 million ad campaign to put pressure on vulnerable Senate Republicans in battleground states to support a quick confirmation when President Trump announces his Supreme Court nominee.

The big picture: "Follow Precedent," previewed by Axios, is one of the first national and cable television ads to run following Justice Ruth Bader Ginsberg's death Friday.