How the Pfizer-Alzheimer's story may have been overblown
The Washington Post's story this week on how Pfizer opted out of pursuing a link between one of its blockbuster drugs and Alzheimer's prevention may have been overblown, Derek Lowe writes in Science Translational Medicine's blog.
The state of play: Undertaking an Alzheimer's trial is a huge endeavor, Lowe argues, and is both risky and expensive. "The clinical success rate for Alzheimer's trials is arguably zero per cent," he writes.
- Thus, the data from Pfizer's insurance claims aren't enough to launch an ambitious clinical trial.
- It's also illogical to think that a drug company would have sat on a potential Alzheimer's prevention — which would be worth a fortune.
- The link between anti-inflammatory drugs and Alzheimer's has been explored before, meaning that it's not like Pfizer kept completely ground-breaking information secret.