Vice President JD Vance told reporters today that the Trump administration's main goal in Iran is preventing nuclear proliferation in the Middle East and beyond, Alex Fitzpatrick and Avery Lotz report.

• Vance, taking questions in a jam-packed and sometimes raucous Brady Press Briefing Room: "Iran would really be the first domino, and that would set off a nuclear arms race all over the world. That's very, very bad for the safety of our country."

☢️ Vance added: "We are not going to have a deal that allows the Iranians to have a nuclear weapon, so as the president just told me, we're locked and loaded."

• "We don't want to go down that pathway, but the president is willing and able to go down that pathway if we have to."
• President Trump convened a meeting on Iran with his top national security team last night that included a briefing on military options, Axios' Barak Ravid reports. Go deeper.

🙋‍♀️ Vance, using a "cheat sheet" to call on reporters while subbing for White House Press Secretary Karoline Leavitt, also took questions on the DOJ's controversial new "anti-weaponization fund," President Trump's surprise endorsement of Texas AG Ken Paxton over Sen. John Cornyn and more.

• On the taxpayer-funded $1.776 billion IRS fund, and the possibility that some of that money could go to Jan. 6 defendants: "You've got to actually look at this stuff and figure out what were they accused of. ... Maybe they had their entire lives ruined in a totally disproportionate way. That's fundamentally illegitimate and political."
• On Trump's endorsement: "I've known John Cornyn for a long time, but unfortunately, when it really counted, Ken Paxton was there for the country, was there for the president, and that's why he ultimately earned the president's endorsement."

Watch Vance's briefing.

President Trump recently disclosed more than 3,500 stock trades made on his behalf in the first quarter, Axios' Emily Peck writes.

• At least $1 million each was purchased in shares of Nvidia, Oracle, Microsoft, Boeing and more.

💸 All told, there were hundreds of millions of dollars' worth of transactions, the Financial Times reports (🔐).

• It's unclear how much money the president earned (or lost).

🤳 Trump critics pounced on the disclosure as an indication of wrongdoing — pointing to the timing of certain trades around key announcements or social media posts.

• A Trump Organization spokesperson tells Axios: "President Trump's investment holdings are maintained exclusively through fully discretionary accounts independently managed by third-party financial institutions with sole and exclusive authority over all investment decisions."

Go deeper.

1. 🏗️ President Trump showed off progress at his planned White House ballroom this morning, calling the building "drone-proof" and a "shield that will totally protect what's going on downstairs." The Senate parliamentarian recently rejected $1 billion in proposed funding for the ballroom and other security upgrades as part of a GOP budget bill. Watch a clip.
2. ☪️ Yesterday's fatal shooting at a San Diego mosque came after some community members long feared violence. Three men were killed, while two teenage suspects were found dead nearby. Get the latest ... More from Axios' Claire Trageser.
3. 🤖 Andrej Karpathy, one of the world's best-known AI researchers and a founding member of OpenAI, is joining rival Anthropic in a major coup. Go deeper.
4. 🏈 Nashville will host the Super Bowl in 2030, a crowning achievement for the city's hospitality industry. More from Axios' Nate Rau.

One of Amtrak's new Airo trains arrived at Seattle's King Street Station during a test run this past weekend, Axios Seattle's Melissa Santos reports.

• The trains — which should start carrying passengers later this year — can travel up to 125 mph.

They'll run on routes including the Cascades, Northeast Regional, Empire Service and more.

• All aboard!