The Food and Drug Administration has significantly escalated its response to the opioid epidemic, saying it wants one particularly powerful drug — called Opana — pulled from the market entirely. The FDA asked Endo Pharmaceuticals on Thursday to withdraw the drug on its own, and said it would revoke the drug's approval if the company doesn't comply.

Opana was linked to a large HIV outbreak last year in a small Indiana town, after users began injecting Opana intravenously. The FDA said it's concerned that the drug's benefits no longer outweigh its risks, "not only for its intended patient population but also in regard to its potential for misuse and abuse."

Why it matters: This is a big step in the opioid crisis. It's the first time the FDA has sought to completely pull an actively marketed opioid off of pharmacies' shelves — and a sign that the new FDA Commissioner, Scott Gottlieb, is willing to treat drug companies as part of the problem.

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Updated 17 mins ago - World

China says U.S. is "endangering peace" with high-level visit to Taiwan

Health and Human Services Secretary Alex Azar during a June briefing in Washington, DC. Photo: Joshua Roberts/Getty Images

Health and Human Services Secretary Alex Azar announced Tuesday night he will lead a delegation to Taiwan "in the coming days."

Why it matters: It's the highest-level visit by a U.S. cabinet official to Taiwan since 1979. Azar is also the first U.S. Cabinet member to visit the island state in six years. The visit has angered China, which views Taiwan as part of its territory. Chinese officials accused the U.S. early Wednesday of "endangering peace" with the visit, AFP reports.

Updated 1 hour ago - Politics & Policy

Coronavirus dashboard

Illustration: Sarah Grillo/Axios

  1. Global: Total confirmed cases as of 3:30 a.m. ET: 18,543,662 — Total deaths: 700,714 — Total recoveries — 11,143,031Map.
  2. U.S.: Total confirmed cases as of 3:30 a.m. ET: 4,771,236 — Total deaths: 156,807 — Total recoveries: 1,528,979 — Total tests: 57,543,852Map.
  3. States: New York City health commissioner resigns in protest of De Blasio's coronavirus response — Local governments go to war over schools.
  4. Public health: 59% of Americans support nationwide 2-week stay-at-home order in NPR poll.
  5. Politics: Trump's national security adviser returns to work after coronavirus recovery Republicans push to expand small business loan program.
  6. Sports: Indy 500 to be held without fansRafael Nadal opts out of U.S. Open.
Updated 2 hours ago - World

At least 100 killed, 4,000 injured after massive explosion rocks Beirut

Photo: Anwar Amro/AFP via Getty Images

A major explosion has slammed central Beirut, Lebanon, damaging buildings as far as several miles away and injuring scores of people.

Driving the news: At least 100 people have been killed and over 4,000 injured in the blast — and the death toll is likely to rise, the Lebanese Red Cross said, per AP. Prime Minister Hassan Diab said the explosions occurred at a warehouse that had been storing 2,750 tons of ammonium nitrate for the past six years.