
Illustration: Lindsey Bailey/Axios
Venture Capital
- T-Therapeutics, a U.K. developer of T-cell therapies for cancer and autoimmune diseases, raised $133m in Series B funding. Advent Life Sciences and British Business Bank led, joined by JJDC, Samsara BioCapital, M Ventures, Eli Lilly and insiders Sofinnova Partners, F-Prime, Digitalis Ventures, Cambridge Innovation Capital, Sanofi Ventures, Tencent, and BGF. Go deeper
- Alethio Therapeutics, a U.K. developer of therapies for myeloproliferative neoplasms, raised $90m in Series A financing. Sofinnova Partners and RA Capital led, joined by Oxford Science Enterprises, Cancer Research Horizons, and the University of Oxford. Go deeper
- Tolerance Bio, a Philadelphia-based immune biotech, is raising an $80m Series A. Go deeper
- Anaheim Bio, a Dutch arthritis biotech, raised a €40m Series A from Droia Ventures, Frazier Life Sciences, RTW, Novartis Venture Fund, RV Invest, and Thuja Capital. Go deeper
- Specific Biologics, a Toronto-based gene-editing therapies company, raised $35m in Series A funding led by Hatteras Venture Partners. Lumira Ventures and adMare BioInnovations, Genesys Capital, Business Development Bank of Canada's (BDC) Life Sciences Venture Fund, DeepWork Capital and Seido Capital joined. Go deeper
- nPhase, an Atlantic Beach, Fla.-based clinical data platform, raised $30m in Series D funding led by Viking Global Investors. Go deeper
- Thryv Therapeutics, an SF-based heart failure biotech, raised $30m in Series B funding. InClin led, joined by Amplitude Ventures, Investissement Québec, Lumira Ventures, adMare BioInnovations, CTI Life Sciences Fund, and Alexandria Venture Investments. Go deeper
- Bit.bio, a British synthetic biology platform, raised $25m in Series D funding from M&G Investments and Abcam founder Jonathan Milner. Go deeper
- Biograil, a Copenhagen-based therapeutic oral device developer, raised €20m from Verve Ventures and Megatrend Invest. Go deeper
- Vitroscope, a Norwegian live-tissue platform, raised $7m in seed funding. Cerberus Ventures and YZR Capital led, joined by Arcas Ventures, Golden Egg Check, and Devico Invest. Go deeper
Private Equity
- Cinven agreed to buy Theramex, a London-based pharma company focused on women's health, from PAI Partners and Carlyle for €2.6b. Go deeper
- GrowthCurve Capital acquired a majority stake in TailorMed, a medication access, affordability, and adherence platform. Go deeper
Public Offerings
- Rezera, a Boston-based biotech focused on inflammatory diseases, set IPO terms to 16.7m shares at $11-$13. It would have a $254m fully diluted valuation at the midpoint, and plans to list on the Nasdaq (RZRA). The Phase 3 biotech has raised $150m from firms like Novo Holdings, Blue Owl, 5AM Ventures, F-Prime, Epidarex Capital, and Sofinnova Capital. Go deeper
Liquidity Events
- AstraZeneca (NYSE: AZN) last month offered to buy Rhythm Pharmaceuticals (Nasdaq: RYTM) for around $10b, or $124 per share, per multiple reports. Go deeper
M&A
- Karyopharm Therapeutics, a Newton, Mass.-based blood cancer biotech, filed for Chapter 11 bankruptcy and plans to merge with Ayrmid, the parent company of Naples, Fla.-based hematology biotech Gamid Cell. Go deeper
- Lonza (Swiss: LONN) agreed to acquire five CDMO manufacturing sites in the U.S. from Merck KGaA. Go deeper
Licensing & Collaboration Agreements
- Biograil, a Copenhagen-based therapeutic oral device developer, raised €20m from Verve Ventures and Megatrend Invest. Go deeper
- Evommune, a Palo Alto, Calif.-based inflammatory disease biotech, will pay $30m upfront and up to $1.1b to Chinese drugmaker Hinova Pharmaceuticals to in-license a molecular glue degrader. Go deeper
Fundraising
- Yosemite, an oncology-focused VC firm led by Reed Jobs, raised $350m for its second fund. Go deeper
It's Personnel
- Andrew Glass, former Vivasure Medical CEO, joined Netherlands-based immune biotech Trained Therapeutix Discovery as CEO. Go deeper
- Cecile Guegan was named CFO at Pfizer (NYSE: PFE) after serving in the role on an interim basis since August. Go deeper
- Damon Daulerio, former senior director of regulatory affairs at Insmed Incorporated, joined Nanoscope Therapeutics as executive director of regulatory affairs. Go deeper
- Dan Janiak, AstraZeneca's former exec director of business development, was named chief business officer at Rockville, Md.-based cancer and immune biotech OncoC4. Go deeper
- Dean Hakanson, former head of U.S. medical affairs at Gilead, joined West Palm Beach, Fla.-based GOA Therapeutics as chief medical officer. Go deeper
