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Win McNamee/Getty Images

Negotiators are set to miss today's deadline for a consensus on NAFTA. Four days after President Trump announced an "understanding" with Mexico, talks aimed at getting Canada on board have broken off and will resume next Wednesday.

Behind the scenes: Trump's off-the-record comments that he would not offer Canada any concessions, which leaked and were reported by the Toronto Star, added a dose of drama. U.S. Trade Representative Robert Lighthizer says Trump has notified Congress that he plans to move ahead with a bilateral deal with Mexico, while leaving open the possibility of Canada joining. Trade experts say the bilateral approach has virtually no chance of success. But by notifying Congress today Trump leaves open the possibility of signing an agreement before a new leftist government takes office in Mexico.

Go deeper

Felix Salmon, author of Capital
7 mins ago - Economy & Business

How the pandemic caused a corporate rebound

Illustration: Sarah Grillo/Axios

WeWork becomes a public company today worth more than $9 billion — a vindication of the expensive turnaround strategy employed after it spectacularly imploded in 2019. Like many companies that find themselves at death's door, that which didn't kill them made them stronger.

Why it matters: Hertz, Alamo Drafthouse, Airbnb, and Toast are among the currently-thriving companies that were shaken to the core in the early days of the pandemic — providing further evidence for the theory that, in the words of former Fast Company editor Bill Taylor, "companies can't be great unless they've almost failed."

37 mins ago - Health

Aduhelm is bombing

The average list price of Aduhelm is roughly $4,300 per monthly infusion. Photo: Biogen

Biogen sold $300,000 worth of Aduhelm in the third quarter, well below Wall Street's expectations, which prompted analysts at Raymond James to call the Alzheimer's drug "potentially the worst drug launch of all time" amid Biogen's "persistent hyperbole about the drug's purported benefits."

The big picture: Aduhelm's controversial approval and high price tag have shaped the market reaction. Health insurers are hesitant to cover Aduhelm until Medicare makes a decision next year, and doctors aren't embracing the drug either.

37 mins ago - Health

COVID cases and deaths keep falling

Expand chart
Data: N.Y. Times; Cartogram: Kavya Beheraj/Axios

America’s coronavirus outbreak is rapidly improving as the Delta wave recedes, and vaccines for kids — which could become available within weeks — will help the situation improve even further.

By the numbers: Nationwide, the U.S. is now averaging about 79,000 new cases per day — a 22% drop over the past two weeks.