The EU this week tightened its antitrust screws on tech companies, announcing that it now will consider the impacts of free products and "digital ecosystems."

Why it matters: Antitrust disputes often boil down to how markets get defined, and this move broadly expands those definitions in Europe.

Details: This is an update to the EU's Market Definition Notice, a rule first passed in 1997 to help European regulators determine if a company has enough market power to create anticompetitive conditions and/or control prices.

• As Reuters' Foo Yun Chee writes: "[It] follows criticism from lawyers and academics that the European Union's antitrust and merger laws have failed to keep up with the times, especially in tech markets and with companies offering free products or services in exchange for users' data."
• Or, as EU antitrust chief Margrethe Vestager put it: "A lot can happen in 25 years, as most of us realize when we look at old pictures of ourselves."

The domestic picture: U.S. antitrust regulators don't have this sort of authority, no matter the expansive philosophies of some current officials.

• But they'll get to indirectly benefit, since the new EU rules are most likely to be applied to global tech giants.
• For example, think about how EU regulators just stopped U.S.-based Amazon from buying U.S.-based iRobot, without the FTC having to lift a legal finger. And that was before the European merger cops gained new powers.

The bottom line: Global deal activity is on the rise, but so is global deal scrutiny.

Owens Corning (NYSE: OC) has agreed to buy Tampa, Fla.-based doormaker Masonite (NYSE: DOOR) for $3.9 billion in cash, or $133 per share.

Why it's the BFD: Masonite shareholders must be feeling the sort of M&A whiplash that can only be soothed by a 38% stock price premium.

Backstory: Less than two months ago, Masonite agreed to buy rival PGT Innovations (NYSE: PGTI) in a $3 billion deal that it called "transformative."

• Then, just weeks later, PGT received and accepted a superior offer from Koch-backed Miter Brands.
• Masonite was left out in the cold, and prone to a takeover attempt.

The bottom line: Ohio-based Owens Corning says that acquisition of Masonite, a 99-year-old company with over 10,000 employees, will strengthen its position in the residential building materials market.

⚡ Koloma, a Denver-based geologic hydrogen startup, raised $245m in Series B funding, per Axios Pro. Khosla Ventures led, and was joined by United Airlines Ventures and Amazon's climate fund. https://axios.link/49lovPu

🚑 Neurona Therapeutics, an SF-based biotech focused on repairing dysfunctional neural circuits, raised $120m. Viking Global and Cormorant co-led, and were joined by The Column Group, LYFE Capital, Schroders Capital, Willett Advisors, Ysios Capital Partners, Euclidean Capital, SymBiosis, Alexandria Venture Investments, Berkeley Frontier Fund, Sphera Biotech Master Fund, Spur Capital Partners, UCB Ventures, and UC Investments. https://axios.link/3urlPAU

🚑 Unlearn, an SF-based platform for creating "digital twins" of clinical trial participants, raised $50m in Series C funding. Altimeter Capital led, and was joined by Insight Partners, 8VC, DCVC, DCVC Bio and insiders Radical Ventures, Wittington Ventures, Mubadala Capital, Epic Ventures, and Necessary VC. https://axios.link/3SRJRyf

• Xensam, a Stockholm-based software asset management provider, raised $40m from Expedition Growth Capital. It's the 8-year-old company's first outside funding round. https://axios.link/3SPVXIj

🚑 Aizon, an SF-based AI startup focused on pharma manufacturing, raised $20m in Series C funding. NewVale Capital led, and was joined by insiders Atlantic Bridge, Crosslink Capital, and Uncork Capital. www.aizon.ai

🚑 Headlight, a San Diego-based mental health startup, raised $18m c0-led by Matrix and Epic Ventures. www.headlight.health

• Shepherd, an SF-based commercial insurtech, raised $13.5m in Series A funding. Costanoa Ventures led, and was joined by Intact Ventures, Era Ventures, Greenlight Re, and Spark Capital. www.shedherdinsurance.com

• Glass Imaging, a Los Altos, Calif.-based startup focused on improving image quality on smartphone cameras, raised $9.3m in seed extension funding. GV led, and was joined by Future Ventures, Abstract Ventures, and LDV Capital. www.glass-imaging.com

🚑 Lili, a British wellbeing monitoring solution for care workers, raised £8.2m in Series A funding led by West Hill Capital. https://axios.link/3OCgYn4

• MediConCen, a Hong Kong-based insurance claims automation startup, raised $6.9m in Series A funding. HSBC Asset Management led, and was joined by G&M Capital, ParticleX and Wings Capital Ventures. https://axios.link/3HQFIUX

• Odyssey, maker of a mushroom-based energy drink, raised $6m from backers like Richard Laver (Rocket Beverage Group) and insider Trinity Ventures. www.odysseyelixir.com

• Omega, a Miami-based bitcoin yield company, raised $6m from Lightspeed Faction, Borderless Capital, Wormhole Cross-Chain Ecosystem Fund, and Bankless Ventures. www.omega.xyz

• Perigon, an Austin, Texas-based contextual intelligence startup, raised $5m in seed funding led by LiveOak Venture Partners. www.goperigon.com

• Cashinvoice, an Indian supply chain finance platform, raised $3.4m in Series A funding from Pravega Ventures, HDFC Bank, and Accion Venture Lab. https://axios.link/3ODPCxc

• Pluto.markets, a Danish challenger neobroker, raised $2.6m led by Magnetic. https://axios.link/3HSSNgE

• Axiology, a Lithuanian DLT securities trading and settlement infrastructure startup, raised €2m co-led by Baltic Sandbox Ventures and Coinvest Capital. https://axios.link/42CBbPM

• Claure Group acquired less than a 5% stake in tech-focused investment firm Hedosophia. https://axios.link/3OZiHDx

• CVC Capital Partners and Haveli Investments acquired British video game maker Jagex from Carlyle for a reported $1.1b. https://axios.link/3UFGhsB

• Georgia Metals, a portfolio company of CID Capital, acquired Watson Metals, a Manchester, Tenn.-based provider of metal roofing, pole barns, and pre-engineered steel buildings. www.georgiametals.com

• Greater Sum Ventures acquired a majority stake in SOMA Global, a Tampa, Fla.-based provider of public safety management software. www.somaglobal.com

🚑 Linden Capital Partners of Chicago is partnering with Ontario Teachers' Pension Plan to launch a new investment platform focused on the "clinical research ecosystem." https://axios.link/3uBBy06

🚑 Spectrum Science, a health care consultancy backed by Knox Lane, acquired clinical trial recruitment company Continuum Clinical. www.spectrumscience.com

• Verlinvest invested in Cible Skin, a French skincare brand. https://axios.link/49wKV09

• BBB Foods, operator of more than 2,200 discount groceries in Mexico, raised $589m in its IPO after revising its terms upwards. It will list on the NYSE (TBBB). https://axios.link/485z2Nu

🚑 Metagenomi, an Emeryville, Calif.-based gene editing startup, raised $94m in its IPO. It priced at the low end of its $14-$17 range, will list on the Nasdaq (MGX), and had raised around $390m in VC funding from firms like Bayer (12.97% pre-IPO stake), Humboldt Fund (6.07%), Sozo Ventures (5.64%), and Moderna (5.47%). https://axios.link/483zPhZ

⚡ Devon Energy (NYSE: DVN) is in talks to buy Calgary-based driller Enerplus (TSX: ERF), per Reuters. https://axios.link/49rX8mD

• Fremantle, a Bertelsmann subsidiary, acquired a majority stake in Beach House Pictures, a Singapore-based production studio. https://axios.link/3uy4zK7

• Tesco (LSE: TSCO), a British grocer, agreed to sell much of its banking business to Barclays (LSE: BARC) for around £600m. https://axios.link/3wcXHm9

• Vontobel of Switzerland agreed to acquire a "significant minority stake" in Ancala Partners, a London-based private infrastructure firm. https://axios.link/497AjoE

• Ares Management raised A$2.6b for an Australian private credit fund. https://axios.link/3UxkFhO

• Warburg Pincus is targeting $2.5b for its third financial services PE fund, per Bloomberg. https://axios.link/3OEjt8v

• AE Industrial Partners named Chris Emerson as senior partner and head of a new Washington, D.C., office. He had been an operating partner with the firm, before which he was CEO of Airbus U.S. Space & Defense. www.aeroequity.com

• CapitalG, Alphabet's growth equity fund, promoted Alex Nichols and Mo Jomaa to partners and Manmeet Gujral and Kelly Barton to VPs. It also hired former Carta CMO Jane Alexander as a partner. www.capitalg.com

• Incline Equity Partners of Pittsburgh promoted Scott Dimond and Kevin Jones to managing directors, Nav Ghuman to director, and Julia Sipos to VP. www.inclineequity.com

Remember when crypto ads seemed to dominate the Super Bowl? Well, seems that's as anachronistic as the Patriots dominating the Super Bowl (yes, that one really hurt to write).

• This year, expect lots of health food and beauty brands that are aimed at the Taylor Swift demographic.
• Plus, the Clydesdales are back.

More football: KC Chiefs owner Clark Hunt this week seemed to tacitly endorse the idea of private equity investment in NFL clubs, which is currently banned.