Illustration: Rebecca Zisser/Axios

Editing cell genomes with CRISPR-Cas9 might increase the risk of developing cancer, two studies published Monday warn, STAT News reports.

Why it matters: The goal of altering cells with CRISPR, a gene-editing tool, is to treat disease, not cause it. If these new results hold up, they could present an insurmountable roadblock for the development of certain CRISPR-based therapies. They are unlikely to stop all CRISPR-based treatment, however.

  • Already, stocks for CRISPR Therapeutics, Editas Medicine, Intellia Therapeutics, and Sangamo Therapeutics have tanked over the reports. These companies are developing treatments for diseases based on the CRISPR techniques the two studies call into question.

The science: The results of these studies likely only apply to one way that CRISPR Cas9 edits genomes, when it replaces disease-causing DNA with modified, healthy versions, per STAT News. It is possible the results don’t apply to another method, which cuts DNA out.

  • What they’re saying: The results are “plausible,” the CEO of CRISPR Therapeutics, Sam Kulkarni, told STAT.

Trend: It’s not the first time CRISPR has run into trouble. A claim in a paper last year that CRISPR caused many off-target side-effects was retracted over interpretations of data, and a report that that humans may be immune to Cas9 was determined to be something that could be worked around.

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Coronavirus dashboard

Illustration: Aïda Amer/Axios

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  2. U.S.: Total confirmed cases as of 12:15 p.m. ET: 5,324,930 — Total deaths: 168,703 — Total recoveries: 1,796,326 — Total tests: 65,676,624Map.
  3. Health: The coronavirus-connected heart ailment that could lead to sudden death in athletes — Patients grow more open with their health data during pandemic.
  4. States: New York to reopen gyms, bowling alleys, museums.
  5. Business: How small businesses got stiffed — Unemployment starts moving in the right direction.
  6. Politics: Biden signals fall strategy with new ads.

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Vice presidential hopeful Sen. Kamala Harris (D-Calif.) Photo: Drew Angerer/Getty Images

When Democrats next week formally nominate the daughter of an Indian immigrant to be vice president, it'll be perhaps the biggest leap yet in the Indian American community's rapid ascent into a powerful political force.

Why it matters: Indian Americans are one of the fastest-growing, wealthiest and most educated demographic groups in the U.S. Politicians work harder every year to woo them. And in Kamala Harris, they'll be represented in a major-party presidential campaign for the first time.

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Illustration: Annelise Capossela/Axios

Cardiologists are increasingly concerned that coronavirus infections could cause heart complications that lead to sudden cardiac death in athletes.

Why it matters: Even if just a tiny percentage of COVID-19 cases lead to major cardiac conditions, the sheer scope of the pandemic raises the risk for those who regularly conduct the toughest physical activity — including amateurs who might be less aware of the danger.