Jan 19, 2018

Doctors to use gene-editing tool to combat cancer

Multiple Myeloma cancer. Section View Of The Bone Marrow. BSIP/UIG Via Getty Images

Doctors at the University of Pennsylvania will soon utilize the gene-editing tool CRISPR to try to combat cancer, per the MIT Tech Review.

Why it matters: The trial combines gene-editing and immunotherapy, two promising areas of medical research. There is a lot of anticipation about human trials involving CRISPR but there have been delays.

The details: The study will reportedly involve 18 patients with multiple myeloma, sarcoma, and melanoma cancers. The researchers plan to modify the patient's immune cells to make them better at finding and attacking the cancer. By modifying the cells outside of the body, and then infusing them back into the patient's blood, the researchers hope to avoid some of CRISPR's potential side-effects. It is still unclear when the trial will start.

Go deeper

Boris Johnson moved to intensive care as coronavirus symptoms worsen

Photo: Peter Summers/Getty Images

U.K. Prime Minister Boris Johnson has been taken to the intensive care unit of St. Thomas Hospital in London due to increasingly severe coronavirus symptoms.

The backdrop: Johnson was admitted to the hospital on Sunday for what Downing Street called "routine tests" because his condition had not improved ten days after he tested positive for the virus. His condition has since "worsened," according to a statement, and Foreign Secretary Dominic Raab will step into his place "where necessary."

StatementArrow13 mins ago - World

Coronavirus dashboard

Illustration: Sarah Grillo/Axios

  1. Global: Total confirmed cases as of 3 p.m. ET: 1,309,439 — Total deaths: 73,703 — Total recoveries: 273,546Map.
  2. U.S.: Total confirmed cases as of 3 p.m. ET: 352,546 — Total deaths: 10,389 — Total recoveries: 18,953Map.
  3. 2020 update: Wisconsin governor issues executive order to delay in-person primary voting until June.
  4. Public health latest: Asymptomatic children could play important role in coronavirus spread, new data from the CDC shows.
  5. States' latest: West coast states send ventilators to New York and other states experiencing a more immediate need — Data suggests coronavirus curve may be flattening in New York, Gov. Andrew Cuomo said.
  6. Jobs latest: Unemployment could already be at 13% "and moving higher," per former Federal Reserve Chair Janet Yellen.
  7. What should I do? Pets, moving and personal health. Answers about the virus from Axios expertsWhat to know about social distancingQ&A: Minimizing your coronavirus risk.
  8. Other resources: CDC on how to avoid the virus, what to do if you get it.

Subscribe to Mike Allen's Axios AM to follow our coronavirus coverage each morning from your inbox.

Wisconsin governor issues order to delay in-person primary voting until June

Tony Evers. Photo: Nuccio DiNuzzo/Getty Images

Wisconsin Gov. Tony Evers (D) issued an executive order Monday delaying in-person voting for the state's primary election — currently scheduled for Tuesday — until June 9.

Why it matters: Wisconsin was slated to be the only state to vote on Tuesday amid the coronavirus pandemic, despite having a stay-at-home order in place.

Go deeperArrow2 hours ago - Health