Jan 8, 2018

Celgene buying cancer drug startup for up to $7 billion

Dan Primack, author of Pro Rata

ccPixs.com / Flickr Creative Commons

Celgene on Monday said that it has agreed to acquire cancer drug startup Impact Biomedicines for upwards of $7 billion.

Why it matters: Because this is a silly stupendous return on investment for Medicxi Ventures, which was the sole participant in Impact's $22.5 million Series A funding round.

That deal was done just over a year ago, according to Medicxi's Kevin Johnson, even though the press release was held until last October. Johnson says that his firm's binary investment thesis was that the FDA would remove its 2013 clinical trial hold on a Sanifi cast-off candidate called fedratinib and that a sale would shortly follow.

"It was a gamble on our part and it worked," Johnson tells Axios.

Deal details: The $7 billion includes $1.1 billion cash upfront and several types of earn-outs.

D.C. angle: Celgene executive chairman Bob Hugin is considering a U.S. Senate run in New Jersey, per Politico.

Bottom line: "Impact has been developing fedratinib to treat bone-marrow disorders known as myelofibrosis and polycythemia vera that affect blood-cell production in tens of thousands of patients. If approved, fedratinib would challenge a blood-disease drug from Incyte Corp. called Jakafi. Both drugs try to stop an enzyme that plays a key role in producing blood cells and driving the diseases." — WSJ

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George Floyd updates

A protester holds a placard reading "Covid kills People, Racism kills Communities" as they attend a demonstration in Manchester, northern England, on June 6, to show solidarity with the Black Lives Matter movement in the wake of the killing of George Floyd. Photo: Paul Ellis/Contributor.

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Buffalo police officers arrested after shoving 75-year-old protester

Photo: Mike Desmond/WBFO via AP

Two Buffalo police officers were charged with assault on Saturday after a video emerged of them shoving a 75-year-old protester while clearing a demonstration in the wake of George Floyd's killing, AP reports, citing prosecutors.

The state of play: Both officers pleaded not guilty to second-degree assault, and were released without bail. After the law enforcement officers were initially suspended without pay on Friday, all 57 officers on the Buffalo Police Department's Emergency Response Team resigned in a show of support for their fellow officers' suspensions.