Biogen's Alzheimer's failure drove its stock down 29%. Photo: John Tlumacki/The Boston Globe via Getty Images

Biogen and Eisai have ended late-stage trials for an Alzheimer's disease drug, less than a year after the pharmaceutical companies painted a rosy picture of the drug's potential. Biogen's stock plunged 29% on the news.

The big picture: It's always a bad sign when clinical trials are discontinued before data are analyzed. It's an even worse sign for Alzheimer's research and raises questions about whether scientists should abandon the idea that the brain disease is "caused by sticky clumps of protein called amyloid plaques," according to a 2016 story by Stat.

Go deeper

California to independently review FDA-approved coronavirus vaccines

California Gov. Gavin Newsom. Photo: Justin Sullivan/Getty Images

California will "independently review" all coronavirus vaccines approved by the Food and Drug Administration before allowing their distribution, Gov. Gavin Newsom (D) announced at a news conference Monday.

Why it matters: The move that comes days after NAID director Anthony Fauci said he had "strong confidence" in FDA-approved vaccines could cast further public doubt that the federal government could release a vaccine based on political motives, rather than safety and efficacy.

Updated 2 hours ago - Politics & Policy

Coronavirus dashboard

Illustration: Annelise Capossela/Axios

  1. Politics: Trump says if Biden's elected, "he'll listen to the scientists"Trump calls Fauci a "disaster" on campaign call.
  2. Health: Coronavirus hospitalizations are on the rise — 8 states set single-day coronavirus case records last week.
  3. States: Wisconsin judge reimposes capacity limit on indoor venues.
  4. Media: Trump attacks CNN as "dumb b*stards" for continuing to cover pandemic.
  5. Business: Consumer confidence surveys show Americans are getting nervousHow China's economy bounced back from coronavirus.
  6. Sports: We've entered the era of limited fan attendance.
  7. Education: Why education technology can’t save remote learning.
Updated 2 hours ago - Politics & Policy

Microphones will be muted during parts of Thursday's presidential debate

Photos: Jim Watson and Saul Loeb/AFP via Getty Images

The Commission on Presidential Debates adopted new measures on Monday to mute the microphones of President Trump and Joe Biden to allow each candidate two minutes of uninterrupted time per segment during Thursday night's debate.

Why it matters: During September's chaotic debate, Trump interrupted Biden 71 times, while Biden interrupted Trump 22 times.

Get Axios AM in your inbox

Catch up on coronavirus stories and special reports, curated by Mike Allen everyday

Please enter a valid email.

Subscription failed
Thank you for subscribing!